Grimwood S - Search Results

1

Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M₄ Muscarinic Acetylcholine Receptor.

Butler CR, Popiolek M, McAllister LA, LaChapelle EA, Kramer M, Beck EM, Mente S, Brodney MA, Brown M, Gilbert A, Helal C, Ogilvie K, Starr J, Uccello D, Grimwood S, Edgerton J, Garst-Orozco J, Kozak R, Lotarski S, Rossi A, Smith D, O'Connor R, Lazzaro J, Steppan C, Steyn SJ. Butler CR, et al. Among authors: grimwood s. J Med Chem. 2024 Jul 11;67(13):10831-10847. doi: 10.1021/acs.jmedchem.4c00293. Epub 2024 Jun 18. J Med Chem. 2024. PMID: 38888621

2

Benson relaxation technique to address sleep quality and aggression among patients with bipolar type I disorder: A randomized clinical trial study.

Gharehbaghi M, Mirhosseini S, Minaei-Moghadam S, Salari M, Grimwood S, Vaghee S. Gharehbaghi M, et al. Among authors: grimwood s. Heliyon. 2024 May 6;10(9):e30648. doi: 10.1016/j.heliyon.2024.e30648. eCollection 2024 May 15. Heliyon. 2024. PMID: 38765068 Free PMC article.

3

Unexpected changes and associated factors of care burden among caregivers of cancer patients one year after COVID-19 outbreak.

Mirhosseini S, Ameri M, Baraniak A, Grimwood S, Basirinezhad MH, Ebrahimi H. Mirhosseini S, et al. Among authors: grimwood s. Heliyon. 2023 Sep 28;9(10):e20504. doi: 10.1016/j.heliyon.2023.e20504. eCollection 2023 Oct. Heliyon. 2023. PMID: 37842576 Free PMC article.

4

Intensive Care Unit Sluice Room Sinks as Reservoirs and Sources of Potential Transmission of Carbapenem-Resistant Bacteria in a South African Tertiary Care Hospital.

Dheda KR, Centner CM, Wilson L, Pooran A, Grimwood S, Ghebrekristos YT, Oelofse S, Joubert IA, Esmail A, Tomasicchio M. Dheda KR, et al. Among authors: grimwood s. Infect Drug Resist. 2023 Aug 21;16:5427-5432. doi: 10.2147/IDR.S418620. eCollection 2023. Infect Drug Resist. 2023. PMID: 37638062 Free PMC article.

5

Filling Data Gaps in Access to Mental Health and Substance Use Services.

Sabad A, Grimwood S, Foebel A, Davidson MJ. Sabad A, et al. Among authors: grimwood s. Healthc Q. 2023 Apr;26(1):10-13. doi: 10.12927/hcq.2023.27058. Healthc Q. 2023. PMID: 37144695

6

Psychological distress as a predictor of the burden of care in family caregivers of COVID-19 patients in Iran: A community-based cross-sectional study.

Mirhosseini S, Grimwood S, Basirinezhad MH, Montazeri R, Ebrahimi H. Mirhosseini S, et al. Among authors: grimwood s. Health Sci Rep. 2022 Nov 22;5(6):e942. doi: 10.1002/hsr2.942. eCollection 2022 Nov. Health Sci Rep. 2022. PMID: 36439040 Free PMC article.

7

One-year changes in the prevalence and positive psychological correlates of depressive symptoms during the COVID-19 pandemic among medical science students in northeast of Iran.

Mirhosseini S, Grimwood S, Dadgari A, Basirinezhad MH, Montazeri R, Ebrahimi H. Mirhosseini S, et al. Among authors: grimwood s. Health Sci Rep. 2022 Jan 12;5(1):e490. doi: 10.1002/hsr2.490. eCollection 2022 Mar. Health Sci Rep. 2022. PMID: 35036582 Free PMC article.

8

Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres.

Yang Q, Lachapelle EA, Kablaoui NM, Webb D, Popiolek M, Grimwood S, Kozak R, O'Connor RE, Lazzaro JT, Butler CR, Zhang L. Yang Q, et al. Among authors: grimwood s. ACS Med Chem Lett. 2019 May 28;10(6):941-948. doi: 10.1021/acsmedchemlett.9b00106. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223452 Free PMC article.

9

Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors.

Wager TT, Galatsis P, Chandrasekaran RY, Butler TW, Li J, Zhang L, Mente S, Subramanyam C, Liu S, Doran AC, Chang C, Fisher K, Grimwood S, Hedde JR, Marconi M, Schildknegt K. Wager TT, et al. Among authors: grimwood s. ACS Chem Neurosci. 2017 Sep 20;8(9):1995-2004. doi: 10.1021/acschemneuro.7b00155. Epub 2017 Jun 30. ACS Chem Neurosci. 2017. PMID: 28609096

10

Design and Synthesis of γ- and δ-Lactam M₁ Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M₁-Selective PAM with Weak Agonist Activity.

Davoren JE, Garnsey M, Pettersen B, Brodney MA, Edgerton JR, Fortin JP, Grimwood S, Harris AR, Jenkinson S, Kenakin T, Lazzaro JT, Lee CW, Lotarski SM, Nottebaum L, O'Neil SV, Popiolek M, Ramsey S, Steyn SJ, Thorn CA, Zhang L, Webb D. Davoren JE, et al. Among authors: grimwood s. J Med Chem. 2017 Aug 10;60(15):6649-6663. doi: 10.1021/acs.jmedchem.7b00597. Epub 2017 Jul 26. J Med Chem. 2017. PMID: 28598634

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