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Safety concern of recombination between self-amplifying mRNA vaccines and viruses is mitigated in vivo.
Hick TAH, Geertsema C, Nguyen W, Bishop CR, van Oosten L, Abbo SR, Dumenil T, van Kuppeveld FJM, Langereis MA, Rawle DJ, Tang B, Yan K, van Oers MM, Suhrbier A, Pijlman GP. Hick TAH, et al. Among authors: geertsema c. Mol Ther. 2024 Aug 7;32(8):2519-2534. doi: 10.1016/j.ymthe.2024.06.019. Epub 2024 Jun 17. Mol Ther. 2024. PMID: 38894543 Free PMC article.
Effective chikungunya virus-like particle vaccine produced in insect cells.
Metz SW, Gardner J, Geertsema C, Le TT, Goh L, Vlak JM, Suhrbier A, Pijlman GP. Metz SW, et al. Among authors: geertsema c. PLoS Negl Trop Dis. 2013;7(3):e2124. doi: 10.1371/journal.pntd.0002124. Epub 2013 Mar 14. PLoS Negl Trop Dis. 2013. PMID: 23516657 Free PMC article.
Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 Variants.
van Oosten L, Altenburg JJ, Fougeroux C, Geertsema C, van den End F, Evers WAC, Westphal AH, Lindhoud S, van den Berg W, Swarts DC, Deurhof L, Suhrbier A, Le TT, Torres Morales S, Myeni SK, Kikkert M, Sander AF, de Jongh WA, Dagil R, Nielsen MA, Salanti A, Søgaard M, Keijzer TMP, Weijers D, Eppink MHM, Wijffels RH, van Oers MM, Martens DE, Pijlman GP. van Oosten L, et al. Among authors: geertsema c. mBio. 2021 Oct 26;12(5):e0181321. doi: 10.1128/mBio.01813-21. Epub 2021 Oct 12. mBio. 2021. PMID: 34634927 Free PMC article.
40 results