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124 results

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Phosphorothioate DNA modification by BREX Type 4 systems in the human gut microbiome.
Yuan Y, DeMott MS, Byrne SR, Flores K, Poyet M, Groussin M, Microbiome Conservancy G, Berdy B, Comstock L, Alm EJ, Dedon PC. Yuan Y, et al. Among authors: comstock l. bioRxiv [Preprint]. 2024 Jun 3:2024.06.03.597175. doi: 10.1101/2024.06.03.597175. bioRxiv. 2024. PMID: 38895356 Free PMC article. Preprint.
A cryptic plasmid is among the most numerous genetic elements in the human gut.
Fogarty EC, Schechter MS, Lolans K, Sheahan ML, Veseli I, Moore RM, Kiefl E, Moody T, Rice PA, Yu MK, Mimee M, Chang EB, Ruscheweyh HJ, Sunagawa S, Mclellan SL, Willis AD, Comstock LE, Eren AM. Fogarty EC, et al. Among authors: comstock le. Cell. 2024 Feb 29;187(5):1206-1222.e16. doi: 10.1016/j.cell.2024.01.039. Cell. 2024. PMID: 38428395 Free article.
A ubiquitous mobile genetic element disarms a bacterial antagonist of the gut microbiota.
Sheahan ML, Coyne MJ, Flores K, Garcia-Bayona L, Chatzidaki-Livanis M, Sundararajan A, Holst AQ, Barquera B, Comstock LE. Sheahan ML, et al. Among authors: comstock le. bioRxiv [Preprint]. 2023 Aug 26:2023.08.25.553775. doi: 10.1101/2023.08.25.553775. bioRxiv. 2023. Update in: Science. 2024 Oct 25;386(6720):414-420. doi: 10.1126/science.adj9504 PMID: 37662397 Free PMC article. Updated. Preprint.
A pervasive large conjugative plasmid mediates multispecies biofilm formation in the intestinal microbiota increasing resilience to perturbations.
García-Bayona L, Said N, Coyne MJ, Flores K, Elmekki NM, Sheahan ML, Camacho AG, Hutt K, Yildiz FH, Kovács ÁT, Waldor MK, Comstock LE. García-Bayona L, et al. Among authors: comstock le. bioRxiv [Preprint]. 2024 Apr 29:2024.04.29.590671. doi: 10.1101/2024.04.29.590671. bioRxiv. 2024. PMID: 38746121 Free PMC article. Preprint.
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution.
Zhang ZJ, Cole CG, Coyne MJ, Lin H, Dylla N, Smith RC, Waligurski E, Ramaswamy R, Woodson C, Burgo V, Little JC, Moran D, Rose A, McMillin M, McSpadden E, Sundararajan A, Sidebottom AM, Pamer EG, Comstock LE. Zhang ZJ, et al. bioRxiv [Preprint]. 2024 Mar 9:2024.03.08.584156. doi: 10.1101/2024.03.08.584156. bioRxiv. 2024. Update in: Cell Host Microbe. 2024 Oct 9;32(10):1853-1867.e5. doi: 10.1016/j.chom.2024.08.016 PMID: 38496653 Free PMC article. Updated. Preprint.
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution.
Zhang ZJ, Cole CG, Coyne MJ, Lin H, Dylla N, Smith RC, Pappas TE, Townson SA, Laliwala N, Waligurski E, Ramaswamy R, Woodson C, Burgo V, Little JC, Moran D, Rose A, McMillin M, McSpadden E, Sundararajan A, Sidebottom AM, Pamer EG, Comstock LE. Zhang ZJ, et al. Among authors: comstock le. Cell Host Microbe. 2024 Oct 9;32(10):1853-1867.e5. doi: 10.1016/j.chom.2024.08.016. Epub 2024 Sep 17. Cell Host Microbe. 2024. PMID: 39293438
A highly conserved and globally prevalent cryptic plasmid is among the most numerous mobile genetic elements in the human gut.
Fogarty EC, Schechter MS, Lolans K, Sheahan ML, Veseli I, Moore R, Kiefl E, Moody T, Rice PA, Yu MK, Mimee M, Chang EB, Mclellan SL, Willis AD, Comstock LE, Eren AM. Fogarty EC, et al. Among authors: comstock le. bioRxiv [Preprint]. 2023 Mar 25:2023.03.25.534219. doi: 10.1101/2023.03.25.534219. bioRxiv. 2023. Update in: Cell. 2024 Feb 29;187(5):1206-1222.e16. doi: 10.1016/j.cell.2024.01.039 PMID: 36993556 Free PMC article. Updated. Preprint.
124 results