Martin NI - Search Results

1

Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.

Bakker AT, Kotsogianni I, Avalos M, Punt JM, Liu B, Piermarini D, Gagestein B, Slingerland CJ, Zhang L, Willemse JJ, Ghimire LB, van den Berg RJHBN, Janssen APA, Ottenhoff THM, van Boeckel CAA, van Wezel GP, Ghilarov D, Martin NI, van der Stelt M. Bakker AT, et al. Among authors: martin ni. Nat Chem. 2024 Sep;16(9):1462-1472. doi: 10.1038/s41557-024-01516-x. Epub 2024 Jun 19. Nat Chem. 2024. PMID: 38898213 Free PMC article.

2

Dissecting the Binding Interactions of Teixobactin with the Bacterial Cell-Wall Precursor Lipid II.

Chiorean S, Antwi I, Carney DW, Kotsogianni I, Giltrap AM, Alexander FM, Cochrane SA, Payne RJ, Martin NI, Henninot A, Vederas JC. Chiorean S, et al. Among authors: martin ni. Chembiochem. 2020 Mar 16;21(6):789-792. doi: 10.1002/cbic.201900504. Epub 2019 Nov 12. Chembiochem. 2020. PMID: 31552694

3

Cephalosporin Prodrug Inhibitors Overcome Metallo-β-Lactamase Driven Antibiotic Resistance.

van Haren MJ, Tehrani KHME, Kotsogianni I, Wade N, Brüchle NC, Mashayekhi V, Martin NI. van Haren MJ, et al. Among authors: martin ni. Chemistry. 2021 Feb 19;27(11):3806-3811. doi: 10.1002/chem.202004694. Epub 2021 Jan 8. Chemistry. 2021. PMID: 33237604 Free PMC article.

4

A β-hairpin epitope as novel structural requirement for protein arginine rhamnosylation.

Yakovlieva L, Wood TM, Kemmink J, Kotsogianni I, Koller F, Lassak J, Martin NI, Walvoort MTC. Yakovlieva L, et al. Among authors: martin ni. Chem Sci. 2020 Dec 7;12(4):1560-1567. doi: 10.1039/d0sc05823h. Chem Sci. 2020. PMID: 34163919 Free PMC article.

5

A Convenient Chemoenzymatic Preparation of Chimeric Macrocyclic Peptide Antibiotics with Potent Activity against Gram-Negative Pathogens.

Wood TM, Slingerland CJ, Martin NI. Wood TM, et al. Among authors: martin ni. J Med Chem. 2021 Aug 12;64(15):10890-10899. doi: 10.1021/acs.jmedchem.1c00176. Epub 2021 Jul 20. J Med Chem. 2021. PMID: 34283589 Free PMC article.

6

Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains.

van Groesen E, Slingerland CJ, Innocenti P, Mihajlovic M, Masereeuw R, Martin NI. van Groesen E, et al. Among authors: martin ni. ACS Infect Dis. 2021 Sep 10;7(9):2746-2754. doi: 10.1021/acsinfecdis.1c00318. Epub 2021 Aug 13. ACS Infect Dis. 2021. PMID: 34387988 Free PMC article.

7

Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin.

Kotsogianni I, Wood TM, Alexander FM, Cochrane SA, Martin NI. Kotsogianni I, et al. Among authors: martin ni. ACS Infect Dis. 2021 Sep 10;7(9):2612-2619. doi: 10.1021/acsinfecdis.1c00316. Epub 2021 Aug 18. ACS Infect Dis. 2021. PMID: 34406007 Free PMC article.

8

Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens.

Wesseling CMJ, Slingerland CJ, Veraar S, Lok S, Martin NI. Wesseling CMJ, et al. Among authors: martin ni. ACS Infect Dis. 2021 Dec 10;7(12):3314-3335. doi: 10.1021/acsinfecdis.1c00466. Epub 2021 Nov 12. ACS Infect Dis. 2021. PMID: 34766746 Free PMC article.

9

Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy.

Al Ayed K, Ballantine RD, Hoekstra M, Bann SJ, Wesseling CMJ, Bakker AT, Zhong Z, Li YX, Brüchle NC, van der Stelt M, Cochrane SA, Martin NI. Al Ayed K, et al. Among authors: martin ni. Chem Sci. 2022 Feb 23;13(12):3563-3570. doi: 10.1039/d2sc00143h. eCollection 2022 Mar 24. Chem Sci. 2022. PMID: 35432860 Free PMC article.

10

Synthesis and Structure-Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494.

Wade N, Wesseling CMJ, Innocenti P, Slingerland CJ, Koningstein GM, Luirink J, Martin NI. Wade N, et al. Among authors: martin ni. ACS Infect Dis. 2022 Nov 11;8(11):2242-2252. doi: 10.1021/acsinfecdis.2c00459. Epub 2022 Nov 1. ACS Infect Dis. 2022. PMID: 36318734 Free PMC article.

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