Grundy GJ - Search Results

1

Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia.

Hill RM, Li C, Hughes JR, Rocha S, Grundy GJ, Parsons JL. Hill RM, et al. Among authors: grundy gj. J Cell Mol Med. 2024 Jun;28(12):e18482. doi: 10.1111/jcmm.18482. J Cell Mol Med. 2024. PMID: 38899556 Free PMC article.

2

The role of autophagy in hypoxia-induced radioresistance.

Hill RM, Fok M, Grundy G, Parsons JL, Rocha S. Hill RM, et al. Radiother Oncol. 2023 Dec;189:109951. doi: 10.1016/j.radonc.2023.109951. Epub 2023 Oct 12. Radiother Oncol. 2023. PMID: 37838322 Free PMC article. Review.

3

Enhancing radiotherapy outcomes in rectal cancer: A systematic review of targeting hypoxia-induced radioresistance.

Fok M, Hill R, Fowler H, Clifford R, Kler A, Uzzi-Daniel J, Rocha S, Grundy G, Parsons J, Vimalachandran D. Fok M, et al. Clin Transl Radiat Oncol. 2023 Oct 28;44:100695. doi: 10.1016/j.ctro.2023.100695. eCollection 2024 Jan. Clin Transl Radiat Oncol. 2023. PMID: 37961749 Free PMC article.

4

KH-like Domains in PARP9/DTX3L and PARP14 Coordinate Protein-Protein Interactions to Promote Cancer Cell Survival.

Saleh H, Liloglou T, Rigden DJ, Parsons JL, Grundy GJ. Saleh H, et al. Among authors: grundy gj. J Mol Biol. 2024 Feb 15;436(4):168434. doi: 10.1016/j.jmb.2023.168434. Epub 2024 Jan 3. J Mol Biol. 2024. PMID: 38182103 Free PMC article.

5

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma.

Zhou C, Fabbrizi MR, Hughes JR, Grundy GJ, Parsons JL. Zhou C, et al. Among authors: grundy gj. Front Oncol. 2022 Aug 16;12:940377. doi: 10.3389/fonc.2022.940377. eCollection 2022. Front Oncol. 2022. PMID: 36052247 Free PMC article.

6

Base excision repair and its implications to cancer therapy.

Grundy GJ, Parsons JL. Grundy GJ, et al. Essays Biochem. 2020 Oct 26;64(5):831-843. doi: 10.1042/EBC20200013. Essays Biochem. 2020. PMID: 32648895 Free PMC article. Review.

7

Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.

Rulten SL, Grundy GJ. Rulten SL, et al. Among authors: grundy gj. Bioessays. 2017 Mar;39(3). doi: 10.1002/bies.201600209. Epub 2017 Jan 30. Bioessays. 2017. PMID: 28133776 Review.

8

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

Grundy GJ, Polo LM, Zeng Z, Rulten SL, Hoch NC, Paomephan P, Xu Y, Sweet SM, Thorne AW, Oliver AW, Matthews SJ, Pearl LH, Caldecott KW. Grundy GJ, et al. Nat Commun. 2016 Aug 17;7:12404. doi: 10.1038/ncomms12404. Nat Commun. 2016. PMID: 27530147 Free PMC article.

9

The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins.

Grundy GJ, Rulten SL, Arribas-Bosacoma R, Davidson K, Kozik Z, Oliver AW, Pearl LH, Caldecott KW. Grundy GJ, et al. Nat Commun. 2016 Apr 11;7:11242. doi: 10.1038/ncomms11242. Nat Commun. 2016. PMID: 27063109 Free PMC article.

10

One ring to bring them all--the role of Ku in mammalian non-homologous end joining.

Grundy GJ, Moulding HA, Caldecott KW, Rulten SL. Grundy GJ, et al. DNA Repair (Amst). 2014 May;17:30-8. doi: 10.1016/j.dnarep.2014.02.019. Epub 2014 Mar 26. DNA Repair (Amst). 2014. PMID: 24680220 Review.

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