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30 results

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Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial.
Singh D, Brightling CE, Rabe KF, Han MK, Christenson SA, Drummond MB, Papi A, Pavord ID, Molfino NA, Almqvist G, Kotalik A, Hellqvist Å, Gołąbek M, Sindhwani NS, Ponnarambil SS; COURSE study investigators. Singh D, et al. Lancet Respir Med. 2024 Dec 6:S2213-2600(24)00324-2. doi: 10.1016/S2213-2600(24)00324-2. Online ahead of print. Lancet Respir Med. 2024. PMID: 39653044
Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Clinical Trial.
Lancaster L, Cottin V, Ramaswamy M, Wuyts WA, Jenkins RG, Scholand MB, Kreuter M, Valenzuela C, Ryerson CJ, Goldin J, Kim GHJ, Jurek M, Decaris M, Clark A, Turner S, Barnes CN, Achneck HE, Cosgrove GP, Lefebvre ÉA, Flaherty KR; PLN-74809-IPF-202 Trial Investigators. Lancaster L, et al. Am J Respir Crit Care Med. 2024 Aug 15;210(4):424-434. doi: 10.1164/rccm.202403-0636OC. Am J Respir Crit Care Med. 2024. PMID: 38843105 Free PMC article. Clinical Trial.
Interleukin-1 receptor antagonist anakinra as treatment for paradoxical responses in HIV-negative tuberculosis patients: A case series.
van Arkel C, Boeree M, Magis-Escurra C, Hoefsloot W, Carpaij N, van Ingen J, Pegge S, Wielders P, Smeenk F, Aarnoutse R, Netea MG, van Crevel R, van Laarhoven A. van Arkel C, et al. Among authors: wielders p. Med. 2022 Sep 9;3(9):603-611.e2. doi: 10.1016/j.medj.2022.07.001. Epub 2022 Aug 29. Med. 2022. PMID: 36041428 Free article.
Effect of once-daily fluticasone furoate/vilanterol versus vilanterol alone on bone mineral density in patients with COPD: a randomized, controlled trial.
Maltais F, Schenkenberger I, Wielders PLML, Ortiz de Saracho J, Chinsky K, Watkins M, Millar V, Crim C. Maltais F, et al. Among authors: wielders plml. Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620965145. doi: 10.1177/1753466620965145. Ther Adv Respir Dis. 2020. PMID: 33081606 Free PMC article. Clinical Trial.
Design of a randomized controlled trial to evaluate effectiveness of methotrexate versus prednisone as first-line treatment for pulmonary sarcoidosis: the PREDMETH study.
Kahlmann V, Janssen Bonás M, Moor CC, van Moorsel CHM, Kool M, Kraaijvanger R, Grutters JC, Overgaauw M, Veltkamp M, Wijsenbeek MS; Collaborating investigators. Kahlmann V, et al. BMC Pulm Med. 2020 Oct 19;20(1):271. doi: 10.1186/s12890-020-01290-9. BMC Pulm Med. 2020. PMID: 33076885 Free PMC article.
Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD.
Faiz A, Imkamp K, van der Wiel E, Boudewijn IM, Koppelman GH, Brandsma CA, Kerstjens HAM, Timens W, Vroegop S, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Steiling K, Spira A, Lenburg ME, Heijink IH, Postma DS, van den Berge M. Faiz A, et al. Among authors: wielders p. Sci Rep. 2020 Oct 15;10(1):17415. doi: 10.1038/s41598-020-72551-0. Sci Rep. 2020. PMID: 33060632 Free PMC article. Clinical Trial.
Critical Error Frequency and the Impact of Training with Inhalers Commonly used for Maintenance Treatment in Chronic Obstructive Pulmonary Disease.
Collier DJ, Wielders P, van der Palen J, Heyes L, Midwinter D, Collison K, Preece A, Barnes N, Sharma R. Collier DJ, et al. Among authors: wielders p. Int J Chron Obstruct Pulmon Dis. 2020 Jun 9;15:1301-1313. doi: 10.2147/COPD.S224209. eCollection 2020. Int J Chron Obstruct Pulmon Dis. 2020. PMID: 32606640 Free PMC article.
Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD.
Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, Trivedi R, St Rose E, Ballal S, McLaren J, Darken P, Aurivillius M, Reisner C, Dorinsky P; ETHOS Investigators. Rabe KF, et al. N Engl J Med. 2020 Jul 2;383(1):35-48. doi: 10.1056/NEJMoa1916046. Epub 2020 Jun 24. N Engl J Med. 2020. PMID: 32579807 Clinical Trial.
30 results