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Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy.
Patel-Murray NL, Zhang L, Claggett BL, Xu D, Serrano-Fernandez P, Healey M, Wandel S, Chen CW, Jacob J, Xu H, Turner GM, Chutkow W, Yates DP, O'Donnell CJ, Prescott MF, Lefkowitz M, Gimpelewicz CR, Beste MT, Zhao F, Gou L, Desai AS, Jhund PS, Packer M, Pfeffer MA, Redfield MM, Rouleau JL, Zannad F, Zile MR, McMurray JJV, Mendelson MM, Solomon SD, Cunningham JW. Patel-Murray NL, et al. Among authors: xu d, xu h. J Am Heart Assoc. 2024 Jul 2;13(13):e033544. doi: 10.1161/JAHA.123.033544. Epub 2024 Jun 21. J Am Heart Assoc. 2024. PMID: 38904251 Free PMC article. Clinical Trial.
Clinical characteristics of heart failure with reduced ejection fraction patients with rare pathogenic variants in dilated cardiomyopathy-associated genes: A subgroup analysis of the PARADIGM-HF trial.
Barat A, Chen CW, Patel-Murray N, McMurray JJV, Packer M, Solomon SD, Desai AS, Rouleau JL, Zile MR, Attari Z, Zhang C, Xu H, Hartman N, Hon C, Healey M, Chutkow W, O'Donnell CJ, Jacob J, Lefkowitz M, Mendelson MM, Wandel S, Yates D, Gimpelewicz C. Barat A, et al. Among authors: xu h. Eur J Heart Fail. 2023 Aug;25(8):1256-1266. doi: 10.1002/ejhf.2886. Epub 2023 Jun 1. Eur J Heart Fail. 2023. PMID: 37191081 Free article.
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial.
Xu H, Hon C, Kaiser S, Serrano-Fernandez P, Hartmann N, Yates DP, Healey M, Gusev AI, Laramie JM, Kennedy S, Marc P, Ridker PM, Obeidat M, Beste MT, Svensson EC, Madar A. Xu H, et al. Circ Genom Precis Med. 2021 Dec;14(6):e003440. doi: 10.1161/CIRCGEN.121.003440. Epub 2021 Oct 19. Circ Genom Precis Med. 2021. PMID: 34663088 No abstract available.
TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial.
Svensson EC, Madar A, Campbell CD, He Y, Sultan M, Healey ML, Xu H, D'Aco K, Fernandez A, Wache-Mainier C, Libby P, Ridker PM, Beste MT, Basson CT. Svensson EC, et al. Among authors: xu h. JAMA Cardiol. 2022 May 1;7(5):521-528. doi: 10.1001/jamacardio.2022.0386. JAMA Cardiol. 2022. PMID: 35385050 Free PMC article. Clinical Trial.
Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis.
Ruotsalainen SE, Surakka I, Mars N, Karjalainen J, Kurki M, Kanai M, Krebs K, Graham S, Mishra PP, Mishra BH, Sinisalo J, Palta P, Lehtimäki T, Raitakari O; Estonian Biobank Research Team; Milani L; Biobank Japan Project; Okada Y; FinnGen; Palotie A, Widen E, Daly MJ, Ripatti S. Ruotsalainen SE, et al. Commun Biol. 2022 Aug 17;5(1):802. doi: 10.1038/s42003-022-03552-0. Commun Biol. 2022. PMID: 35978133 Free PMC article.
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection.
Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Wang C, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Bhattacharya R, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Kiryluk K, Neale B, Ionita-Laza I, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ; Biobank Japan Project; FinnGen Consortium; Terao C, Zhao H, Ebert BL, Reilly MP, Ganna A, Machiela MJ, Genovese G, Natarajan P. Zekavat SM, et al. Nat Med. 2021 Jun;27(6):1012-1024. doi: 10.1038/s41591-021-01371-0. Epub 2021 Jun 7. Nat Med. 2021. PMID: 34099924 Free PMC article.
Reversal of siRNA-mediated gene silencing in vivo.
Zlatev I, Castoreno A, Brown CR, Qin J, Waldron S, Schlegel MK, Degaonkar R, Shulga-Morskaya S, Xu H, Gupta S, Matsuda S, Akinc A, Rajeev KG, Manoharan M, Maier MA, Jadhav V. Zlatev I, et al. Among authors: xu h. Nat Biotechnol. 2018 Jul;36(6):509-511. doi: 10.1038/nbt.4136. Epub 2018 May 14. Nat Biotechnol. 2018. PMID: 29786096
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