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Page 1
Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis.
Ofoghi A, Kotschi S, Lemmer IL, Haas DT, Willemsen N, Bayer B, Jung AS, Möller S, Haberecht-Müller S, Krüger E, Krahmer N, Bartelt A. Ofoghi A, et al. Among authors: kotschi s. Cell Death Differ. 2024 Oct 9. doi: 10.1038/s41418-024-01398-z. Online ahead of print. Cell Death Differ. 2024. PMID: 39384955
Ferroptosis in health and disease.
Berndt C, Alborzinia H, Amen VS, Ayton S, Barayeu U, Bartelt A, Bayir H, Bebber CM, Birsoy K, Böttcher JP, Brabletz S, Brabletz T, Brown AR, Brüne B, Bulli G, Bruneau A, Chen Q, DeNicola GM, Dick TP, Distéfano A, Dixon SJ, Engler JB, Esser-von Bieren J, Fedorova M, Friedmann Angeli JP, Friese MA, Fuhrmann DC, García-Sáez AJ, Garbowicz K, Götz M, Gu W, Hammerich L, Hassannia B, Jiang X, Jeridi A, Kang YP, Kagan VE, Konrad DB, Kotschi S, Lei P, Le Tertre M, Lev S, Liang D, Linkermann A, Lohr C, Lorenz S, Luedde T, Methner A, Michalke B, Milton AV, Min J, Mishima E, Müller S, Motohashi H, Muckenthaler MU, Murakami S, Olzmann JA, Pagnussat G, Pan Z, Papagiannakopoulos T, Pedrera Puentes L, Pratt DA, Proneth B, Ramsauer L, Rodriguez R, Saito Y, Schmidt F, Schmitt C, Schulze A, Schwab A, Schwantes A, Soula M, Spitzlberger B, Stockwell BR, Thewes L, Thorn-Seshold O, Toyokuni S, Tonnus W, Trumpp A, Vandenabeele P, Vanden Berghe T, Venkataramani V, Vogel FCE, von Karstedt S, Wang F, Westermann F, Wientjens C, Wilhelm C, Wölk M, Wu K, Yang X, Yu F, Zou Y, Conrad M. Berndt C, et al. Among authors: kotschi s. Redox Biol. 2024 Sep;75:103211. doi: 10.1016/j.redox.2024.103211. Epub 2024 May 30. Redox Biol. 2024. PMID: 38908072 Free PMC article. Review.
The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.
Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, Karbiener M, Higareda-Almaraz JC, Khani S, Tews D, Fischer-Posovszky P, Sun W, Dong H, Ghosh A, Wolfrum C, Wabitsch M, Virtanen KA, Blüher M, Nielsen S, Zeigerer A, García-Cáceres C, Scheideler M, Herzig S, Bartelt A. Giroud M, et al. Among authors: kotschi s. EMBO Rep. 2023 Oct 9;24(10):e57600. doi: 10.15252/embr.202357600. Epub 2023 Sep 6. EMBO Rep. 2023. PMID: 37671834 Free PMC article.
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Ziegler KA, Ahles A, Dueck A, Esfandyari D, Pichler P, Weber K, Kotschi S, Bartelt A, Sinicina I, Graw M, Leonhardt H, Weckbach LT, Massberg S, Schifferer M, Simons M, Hoeher L, Luo J, Ertürk A, Schiattarella GG, Sassi Y, Misgeld T, Engelhardt S. Ziegler KA, et al. Among authors: kotschi s. Science. 2023 Jul 21;381(6655):285-290. doi: 10.1126/science.abn6366. Epub 2023 Jul 20. Science. 2023. PMID: 37471539
Author Correction: Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.
Sigmund AM, Winkler M, Engelmayer S, Kugelmann D, Egu DT, Steinert LS, Fuchs M, Hiermaier M, Radeva MY, Bayerbach FC, Butz E, Kotschi S, Hudemann C, Hertl M, Yeruva S, Schmidt E, Yazdi AS, Ghoreschi K, Vielmuth F, Waschke J. Sigmund AM, et al. Among authors: kotschi s. Nat Commun. 2023 Feb 7;14(1):665. doi: 10.1038/s41467-023-36464-6. Nat Commun. 2023. PMID: 36750581 Free PMC article. No abstract available.
Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.
Sigmund AM, Winkler M, Engelmayer S, Kugelmann D, Egu DT, Steinert LS, Fuchs M, Hiermaier M, Radeva MY, Bayerbach FC, Butz E, Kotschi S, Hudemann C, Hertl M, Yeruva S, Schmidt E, Yazdi AS, Ghoreschi K, Vielmuth F, Waschke J. Sigmund AM, et al. Among authors: kotschi s. Nat Commun. 2023 Jan 9;14(1):116. doi: 10.1038/s41467-022-35741-0. Nat Commun. 2023. PMID: 36624106 Free PMC article.
Fire up the pyre: inosine thermogenic signaling for obesity therapy.
Willemsen N, Kotschi S, Bartelt A. Willemsen N, et al. Among authors: kotschi s. Signal Transduct Target Ther. 2022 Nov 11;7(1):375. doi: 10.1038/s41392-022-01218-1. Signal Transduct Target Ther. 2022. PMID: 36357366 Free PMC article. No abstract available.
NFE2L1-mediated proteasome function protects from ferroptosis.
Kotschi S, Jung A, Willemsen N, Ofoghi A, Proneth B, Conrad M, Bartelt A. Kotschi S, et al. Mol Metab. 2022 Mar;57:101436. doi: 10.1016/j.molmet.2022.101436. Epub 2022 Jan 6. Mol Metab. 2022. PMID: 34999280 Free PMC article.
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Blüher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. Giroud M, et al. Among authors: kotschi s. Diabetologia. 2021 Aug;64(8):1850-1865. doi: 10.1007/s00125-021-05470-y. Epub 2021 May 20. Diabetologia. 2021. PMID: 34014371 Free PMC article.