Jücker M - Search Results

1

Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells.

Smit DJ, Brauer H, Horn S, Yigit G, Haider MT, Pogenberg V, Schumacher U, Pantel K, Jücker M. Smit DJ, et al. Among authors: jucker m. Cell Signal. 2024 Sep;121:111270. doi: 10.1016/j.cellsig.2024.111270. Epub 2024 Jun 21. Cell Signal. 2024. PMID: 38909932 Free article.

2

Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases.

Ehm PAH, Linnebacher M, Block A, Rehbach C, Jücker M. Ehm PAH, et al. Among authors: jucker m. Cell Signal. 2023 Aug;108:110720. doi: 10.1016/j.cellsig.2023.110720. Epub 2023 May 18. Cell Signal. 2023. PMID: 37207939

3

Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis.

Kempska J, Oliveira-Ferrer L, Grottke A, Qi M, Alawi M, Meyer F, Borgmann K, Hamester F, Eylmann K, Rossberg M, Smit DJ, Jücker M, Laakmann E, Witzel I, Schmalfeldt B, Müller V, Legler K. Kempska J, et al. Among authors: jucker m. Front Oncol. 2023 Jul 6;13:1129682. doi: 10.3389/fonc.2023.1129682. eCollection 2023. Front Oncol. 2023. PMID: 37483521 Free PMC article.

4

K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3.

Geißert R, Lammert A, Wirth S, Hönig R, Lohfink D, Unger M, Pek D, Schlüter K, Scheftschik T, Smit DJ, Jücker M, Menke A, Giehl K. Geißert R, et al. Among authors: jucker m. Cell Commun Signal. 2024 Jan 30;22(1):85. doi: 10.1186/s12964-024-01484-2. Cell Commun Signal. 2024. PMID: 38291468 Free PMC article.

5

Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway.

Ehm PAH, Horn S, Hoffer K, Kriegs M, Horn M, Giehler S, Nalaskowski M, Rehbach C, Horstmann MA, Jücker M. Ehm PAH, et al. Among authors: jucker m. Cell Commun Signal. 2024 Jul 12;22(1):360. doi: 10.1186/s12964-024-01732-5. Cell Commun Signal. 2024. PMID: 38992657 Free PMC article.

6

Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension-to-Adherent Transition.

Smit DJ, Hoffer K, Bettin B, Kriegs M, Cayrefourcq L, Schumacher U, Pantel K, Alix-Panabières C, Jücker M. Smit DJ, et al. Among authors: jucker m. Cancer Med. 2024 Oct;13(20):e70339. doi: 10.1002/cam4.70339. Cancer Med. 2024. PMID: 39425449 Free PMC article.

7

Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021.

Ehm P, Bettin B, Jücker M. Ehm P, et al. Among authors: jucker m. Biochim Biophys Acta Mol Cell Res. 2023 Jun;1870(5):119467. doi: 10.1016/j.bbamcr.2023.119467. Epub 2023 Mar 21. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 36958526 Free article.

8

Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.

Valdes P, Caldwell AB, Liu Q, Fitzgerald MQ, Ramachandran S, Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Galasko DR, Yuan SH, Wagner SL, Subramaniam S. Valdes P, et al. Alzheimers Res Ther. 2025 Jan 4;17(1):5. doi: 10.1186/s13195-024-01659-6. Alzheimers Res Ther. 2025. PMID: 39754192 Free PMC article.

9

Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer's disease.

Tu JC, Millar PR, Strain JF, Eck A, Adeyemo B, Snyder AZ, Daniels A, Karch C, Huey ED, McDade E, Day GS, Yakushev I, Hassenstab J, Morris J, Llibre-Guerra JJ, Ibanez L, Jucker M, Mendez PC, Perrin RJ, Benzinger TLS, Jack CR Jr, Betzel R, Ances BM, Eggebrecht AT, Gordon BA, Wheelock MD; Dominantly Inherited Alzheimer Network. Tu JC, et al. Among authors: jucker m. Netw Neurosci. 2024 Dec 10;8(4):1265-1290. doi: 10.1162/netn_a_00395. eCollection 2024. Netw Neurosci. 2024. PMID: 39735502 Free PMC article.

10

Sample size estimates for biomarker-based outcome measures in clinical trials in autosomal dominant Alzheimer's disease.

Cash DM, Morgan KE, O'Connor A, Veale TD, Malone IB, Poole T, Benzinger TL, Gordon BA, Ibanez L, Li Y, Llibre-Guerra JJ, McDade E, Wang G, Chhatwal JP, Day GS, Huey E, Jucker M, Levin J, Niimi Y, Noble JM, Roh JH, Sánchez-Valle R, Schofield PR, Bateman RJ, Frost C, Fox NC; Dominantly Inherited Alzheimer Network (DIAN). Cash DM, et al. Among authors: jucker m. medRxiv [Preprint]. 2024 Nov 16:2024.11.12.24316919. doi: 10.1101/2024.11.12.24316919. medRxiv. 2024. PMID: 39606328 Free PMC article. Preprint.

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