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Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease.
Nunes JA, Santos-Júnior PFDS, Gomes MC, Ferreira LAS, Padilha EKA, Teixeira TR, Stanger EJ, Kaur Y, Silva EBD, Costa CACB, Freitas JD, Araújo-Júnior JX, Mendonça-Junior FJB, Giardini MA, Siqueira-Neto JL, Caffrey CR, Zhan P, Cardoso SH, Silva-Júnior EFD. Nunes JA, et al. Among authors: padilha eka. Eur J Med Chem. 2025 Feb 5;283:117109. doi: 10.1016/j.ejmech.2024.117109. Epub 2024 Nov 28. Eur J Med Chem. 2025. PMID: 39653622