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Page 1
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors.
Ridnour LA, Cheng RY, Kedei N, Somasundaram V, Bhattacharyya DD, Basudhar D, Wink AL, Walke AJ, Kim C, Heinz WF, Edmondson EF, Butcher DO, Warner AC, Dorsey TH, Pore M, Kinders RJ, Lipkowitz S, Bryant RJ, Rittscher J, Wong ST, Hewitt SM, Chang JC, Shalaby A, Callagy GM, Glynn SA, Ambs S, Anderson SK, McVicar DW, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: heinz wf. JCI Insight. 2024 May 21;9(12):e165356. doi: 10.1172/jci.insight.165356. JCI Insight. 2024. PMID: 38912586 Free PMC article.
Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density.
Somasundaram V, Ridnour LA, Cheng RY, Walke AJ, Kedei N, Bhattacharyya DD, Wink AL, Edmondson EF, Butcher D, Warner AC, Dorsey TH, Scheiblin DA, Heinz W, Bryant RJ, Kinders RJ, Lipkowitz S, Wong ST, Pore M, Hewitt SM, McVicar DW, Anderson SK, Chang J, Glynn SA, Ambs S, Lockett SJ, Wink DA. Somasundaram V, et al. Redox Biol. 2022 Dec;58:102529. doi: 10.1016/j.redox.2022.102529. Epub 2022 Nov 9. Redox Biol. 2022. PMID: 36375380 Free PMC article.
NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RY, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Kinders RJ, Lipkowitz S, Wong ST, Anderson SK, McVicar DW, Li X, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: heinz wf. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572859. doi: 10.1101/2023.12.21.572859. bioRxiv. 2023. PMID: 38187532 Free PMC article. Preprint.
Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients.
Ridnour LA, Cheng RYS, Heinz WF, Pore M, Gonzalez AL, Femino EL, Moffat R, Wink AL, Imtiaz F, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Wong STC, Lipkowitz S, Glynn S, Vitek MP, McVicar DW, Li X, Anderson SK, Paolocci N, Hewitt SM, Ambs S, Billiar TR, Chang JC, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: heinz wf. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572867. doi: 10.1101/2023.12.21.572867. bioRxiv. 2023. PMID: 38187660 Free PMC article. Preprint.
Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER - Breast Tumors that Lead to Poor Outcome.
Cheng RY, Ridnour LA, Wink AL, Gonzalez AL, Femino EL, Rittscher H, Somasundarum V, Heinz WF, Coutinho L, Cristina Rangel M, Edmondson EF, Butcher D, Kinders RJ, Li X, Wong STC, McVicar DW, Anderson SK, Pore M, Hewitt SM, Billiar TR, Glynn S, Chang JC, Lockett SJ, Ambs S, Wink DA. Cheng RY, et al. Among authors: heinz wf. bioRxiv [Preprint]. 2023 Apr 6:2023.04.06.535916. doi: 10.1101/2023.04.06.535916. bioRxiv. 2023. Update in: Cell Death Dis. 2023 May 11;14(5):319. doi: 10.1038/s41419-023-05834-9 PMID: 37066331 Free PMC article. Updated. Preprint.
Determining structures of RNA conformers using AFM and deep neural networks.
Degenhardt MFS, Degenhardt HF, Bhandari YR, Lee YT, Ding J, Yu P, Heinz WF, Stagno JR, Schwieters CD, Watts NR, Wingfield PT, Rein A, Zhang J, Wang YX. Degenhardt MFS, et al. Among authors: heinz wf. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-07559-x. Online ahead of print. Nature. 2024. PMID: 39695231
Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RYS, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho LL, Moffat RL, Butcher D, Edmondson EF, Li X, Rangel MC, Kinders RJ, Rittscher J, Lipkowitz S, Wong STC, Anderson SK, McVicar DW, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: heinz wf. Cancer Res Commun. 2024 Oct 1;4(10):2766-2782. doi: 10.1158/2767-9764.CRC-24-0235. Cancer Res Commun. 2024. PMID: 39356141 Free PMC article.
Author Correction: Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells.
Il Ahn J, Zhang L, Ravishankar H, Fan L, Kirsch K, Zeng Y, Meng L, Park JE, Yun HY, Ghirlando R, Ma B, Ball D, Ku B, Nussinov R, Schmit JD, Heinz WF, Kim SJ, Karpova T, Wang YX, Lee KS. Il Ahn J, et al. Among authors: heinz wf. Commun Biol. 2023 Jul 27;6(1):784. doi: 10.1038/s42003-023-05162-w. Commun Biol. 2023. PMID: 37500946 Free PMC article. No abstract available.
Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells.
Il Ahn J, Zhang L, Ravishankar H, Fan L, Kirsch K, Zeng Y, Meng L, Park JE, Yun HY, Ghirlando R, Ma B, Ball D, Ku B, Nussinov R, Schmit JD, Heinz WF, Kim SJ, Karpova T, Wang YX, Lee KS. Il Ahn J, et al. Among authors: heinz wf. Commun Biol. 2023 Jul 11;6(1):712. doi: 10.1038/s42003-023-05067-8. Commun Biol. 2023. PMID: 37433832 Free PMC article.
39 results