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Changes in glial cell activation and extracellular vesicles production precede the onset of disease symptoms in transgenic hSOD1G93A pigs.
Golia MT, Frigerio R, Pucci S, Sironi F, Margotta C, Pasetto L, Testori C, Berrone E, Ingravalle F, Chiari M, Gori A, Duchi R, Perota A, Bergamaschi L, D'Angelo A, Cagnotti G, Galli C, Corona C, Bonetto V, Bendotti C, Cretich M, Colombo SF, Verderio C. Golia MT, et al. Among authors: bendotti c. Exp Neurol. 2024 Apr;374:114716. doi: 10.1016/j.expneurol.2024.114716. Epub 2024 Feb 6. Exp Neurol. 2024. PMID: 38331161 Free article.
Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice.
Niccolai E, Di Gloria L, Trolese MC, Fabbrizio P, Baldi S, Nannini G, Margotta C, Nastasi C, Ramazzotti M, Bartolucci G, Bendotti C, Nardo G, Amedei A. Niccolai E, et al. Among authors: bendotti c. Acta Neuropathol Commun. 2024 Nov 6;12(1):174. doi: 10.1186/s40478-024-01877-x. Acta Neuropathol Commun. 2024. PMID: 39506789 Free PMC article.
Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration.
Baindoor S, Gibriel HAY, Venø MT, Su J, Morrissey EP, Jirström E, Woods I, Kenny A, Alves M, Halang L, Fabbrizio P, Bilen M, Engel T, Hogg MC, Bendotti C, Nardo G, Slack RS, Kjems J, Prehn JHM. Baindoor S, et al. Among authors: bendotti c. Dis Model Mech. 2024 Nov 1;17(11):dmm050870. doi: 10.1242/dmm.050870. Epub 2024 Nov 18. Dis Model Mech. 2024. PMID: 39552337 Free PMC article.
Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.
Beghi E, Pupillo E, Bonito V, Buzzi P, Caponnetto C, Chiò A, Corbo M, Giannini F, Inghilleri M, Bella VL, Logroscino G, Lorusso L, Lunetta C, Mazzini L, Messina P, Mora G, Perini M, Quadrelli ML, Silani V, Simone IL, Tremolizzo L; Italian ALS Study Group. Beghi E, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):397-405. doi: 10.3109/21678421.2013.764568. Epub 2013 Feb 19. Amyotroph Lateral Scler Frontotemporal Degener. 2013. PMID: 23421600 Clinical Trial.
Intraspinal stem cell transplantation for amyotrophic lateral sclerosis: Ready for efficacy clinical trials?
Atassi N, Beghi E, Blanquer M, Boulis NM, Cantello R, Caponnetto C, Chiò A, Dunnett SB, Feldman EL, Vescovi A, Mazzini L; attendees of the International Workshop on Progress in Stem Cells Research for ALS/MND. Atassi N, et al. Cytotherapy. 2016 Dec;18(12):1471-1475. doi: 10.1016/j.jcyt.2016.08.005. Epub 2016 Oct 6. Cytotherapy. 2016. PMID: 27720637 Free article.
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amossé Q, Ceyzériat K, Badina AM, Kövari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM, Smith AM, Barnes SJ, Hampton DW, van der Valk P, Jacobson S, Howell OW, Baker D, Kipp M, Kaddatz H, Tournier BB, Millet P, Matthews PM, Moore CS, Amor S, Owen DR. Nutma E, et al. Among authors: bendotti c. Nat Commun. 2023 Aug 28;14(1):5247. doi: 10.1038/s41467-023-40937-z. Nat Commun. 2023. PMID: 37640701 Free PMC article.
199 results