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INF2 mutations cause kidney disease through a gain-of-function mechanism.
Subramanian B, Williams S, Karp S, Hennino MF, Jacas S, Lee M, Riella CV, Alper SL, Higgs HN, Pollak MR. Subramanian B, et al. Among authors: jacas s. Sci Adv. 2024 Nov 15;10(46):eadr1017. doi: 10.1126/sciadv.adr1017. Epub 2024 Nov 13. Sci Adv. 2024. PMID: 39536114 Free PMC article.
A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy.
Pintye D, Sziva RE, Mastyugin M, Young BC, Jacas S, Török M, Salahuddin S, Jagtap P, Southan GJ, Zsengellér ZK. Pintye D, et al. Among authors: jacas s. Biology (Basel). 2023 Sep 12;12(9):1229. doi: 10.3390/biology12091229. Biology (Basel). 2023. PMID: 37759628 Free PMC article.