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Page 1
Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells.
Sparano C, Solís-Sayago D, Zangger NS, Rindlisbacher L, Van Hove H, Vermeer M, Westermann F, Mussak C, Rallo E, Dergun S, Litscher G, Xu Y, Bijnen M, Friedrich C, Greter M, Juranić Lisnić V, Becher B, Gasteiger G, Oxenius A, Tugues S. Sparano C, et al. Among authors: rindlisbacher l. J Exp Med. 2025 Mar 3;222(3):e20240930. doi: 10.1084/jem.20240930. Epub 2024 Dec 18. J Exp Med. 2025. PMID: 39692745
Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice.
Talvard-Balland N, Braun LM, Dixon KO, Zwick M, Engel H, Hartmann A, Duquesne S, Penter L, Andrieux G, Rindlisbacher L, Acerbis A, Ehmann J, Köllerer C, Ansuinelli M, Rettig A, Moschallski K, Apostolova P, Brummer T, Illert AL, Schramm MA, Cheng Y, Köttgen A, Duyster J, Menssen HD, Ritz J, Blazar BR, Boerries M, Schmitt-Gräff A, Sariipek N, Van Galen P, Buescher JM, Cabezas-Wallscheid N, Pahl HL, Pearce EL, Soiffer RJ, Wu CJ, Vago L, Becher B, Köhler N, Wertheimer T, Kuchroo VK, Zeiser R. Talvard-Balland N, et al. Among authors: rindlisbacher l. J Clin Invest. 2024 Jun 25;134(16):e177460. doi: 10.1172/JCI177460. J Clin Invest. 2024. PMID: 38916965 Free PMC article.
IL-23 stabilizes an effector Treg cell program in the tumor microenvironment.
Wertheimer T, Zwicky P, Rindlisbacher L, Sparano C, Vermeer M, de Melo BMS, Haftmann C, Rückert T, Sethi A, Schärli S, Huber A, Ingelfinger F, Xu C, Kim D, Häne P, Fonseca da Silva A, Muschaweckh A, Nunez N, Krishnarajah S, Köhler N, Zeiser R, Oukka M, Korn T, Tugues S, Becher B. Wertheimer T, et al. Among authors: rindlisbacher l. Nat Immunol. 2024 Mar;25(3):512-524. doi: 10.1038/s41590-024-01755-7. Epub 2024 Feb 14. Nat Immunol. 2024. PMID: 38356059 Free PMC article.
NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis.
Marinović S, Lenartić M, Mladenić K, Šestan M, Kavazović I, Benić A, Krapić M, Rindlisbacher L, Cokarić Brdovčak M, Sparano C, Litscher G, Turk Wensveen T, Mikolašević I, Fučkar Čupić D, Bilić-Zulle L, Steinle A, Waisman A, Hayday A, Tugues S, Becher B, Polić B, Wensveen FM. Marinović S, et al. Among authors: rindlisbacher l. Sci Immunol. 2023 Sep 29;8(87):eadd1599. doi: 10.1126/sciimmunol.add1599. Epub 2023 Sep 29. Sci Immunol. 2023. PMID: 37774007 Free PMC article.
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma.
Look T, Puca E, Bühler M, Kirschenbaum D, De Luca R, Stucchi R, Ravazza D, Di Nitto C, Roth P, Katzenelenbogen Y, Weiner A, Rindlisbacher L, Becher B, Amit I, Weller M, Neri D, Hemmerle T, Weiss T. Look T, et al. Among authors: rindlisbacher l. Sci Transl Med. 2023 May 24;15(697):eadf2281. doi: 10.1126/scitranslmed.adf2281. Epub 2023 May 24. Sci Transl Med. 2023. PMID: 37224228
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production.
Langenbach M, Giesler S, Richtsfeld S, Costa-Pereira S, Rindlisbacher L, Wertheimer T, Braun LM, Andrieux G, Duquesne S, Pfeifer D, Woessner NM, Menssen HD, Taromi S, Duyster J, Börries M, Brummer T, Blazar BR, Minguet S, Turko P, Levesque MP, Becher B, Zeiser R. Langenbach M, et al. Among authors: rindlisbacher l. Mol Cancer Res. 2023 Aug 1;21(8):849-864. doi: 10.1158/1541-7786.MCR-22-0898. Mol Cancer Res. 2023. PMID: 37071397 Free PMC article.
Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation.
Ingelfinger F, Sparano C, Bamert D, Reyes-Leiva D, Sethi A, Rindlisbacher L, Zwicky P, Kreutmair S, Widmer CC, Mundt S, Cortés-Vicente E, Tugues S, Becher B, Schreiner B. Ingelfinger F, et al. Among authors: rindlisbacher l. J Allergy Clin Immunol. 2023 Jan;151(1):280-286.e2. doi: 10.1016/j.jaci.2022.09.010. Epub 2022 Sep 16. J Allergy Clin Immunol. 2023. PMID: 36122787 Free article.
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.
Agliardi G, Liuzzi AR, Hotblack A, De Feo D, Núñez N, Stowe CL, Friebel E, Nannini F, Rindlisbacher L, Roberts TA, Ramasawmy R, Williams IP, Siow BM, Lythgoe MF, Kalber TL, Quezada SA, Pule MA, Tugues S, Straathof K, Becher B. Agliardi G, et al. Among authors: rindlisbacher l. Nat Commun. 2021 Jan 19;12(1):444. doi: 10.1038/s41467-020-20599-x. Nat Commun. 2021. PMID: 33469002 Free PMC article.
The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age.
Szécsényi-Nagy A, Roth C, Brandt G, Rihuete-Herrada C, Tejedor-Rodríguez C, Held P, García-Martínez-de-Lagrán Í, Arcusa Magallón H, Zesch S, Knipper C, Bánffy E, Friederich S, Meller H, Bueno Ramírez P, Barroso Bermejo R, de Balbín Behrmann R, Herrero-Corral AM, Flores Fernández R, Alonso Fernández C, Jiménez Echevarria J, Rindlisbacher L, Oliart C, Fregeiro MI, Soriano I, Vicente O, Micó R, Lull V, Soler Díaz J, López Padilla JA, Roca de Togores Muñoz C, Hernández Pérez MS, Jover Maestre FJ, Lomba Maurandi J, Avilés Fernández A, Lillios KT, Silva AM, Magalhães Ramalho M, Oosterbeek LM, Cunha C, Waterman AJ, Roig Buxó J, Martínez A, Ponce Martínez J, Hunt Ortiz M, Mejías-García JC, Pecero Espín JC, Cruz-Auñón Briones R, Tomé T, Carmona Ballestero E, Cardoso JL, Araújo AC, Liesau von Lettow-Vorbeck C, Blasco Bosqued C, Ríos Mendoza P, Pujante A, Royo-Guillén JI, Esquembre Beviá MA, Dos Santos Goncalves VM, Parreira R, Morán Hernández E, Méndez Izquierdo E, Vega Y Miguel J, Menduiña García R, Martínez Calvo V, López Jiménez O, Krause J, Pichler SL, Garrido-Pena R, Kunst M, Risch R, Rojo-Guerra MA, Haak W, Alt KW. Szécsényi-Nagy A, et al. Among authors: rindlisbacher l. Sci Rep. 2017 Nov 15;7(1):15644. doi: 10.1038/s41598-017-15480-9. Sci Rep. 2017. PMID: 29142317 Free PMC article.