Shen G - Search Results

1

Pharmacokinetics, Mass Balance, Safety, and Tolerability of Obeldesivir in Healthy Participants.

Anoshchenko O, Abdelghany M, Lichtman A, Duan R, Chen H, Shaik NA, Peng CC, Yue Q, Subramanian R, Hyland RH, Davies S, Castellanos K, Mak L, Shen G, Xiao D, Caro L, Winter H, Llewellyn J, Humeniuk R. Anoshchenko O, et al. Among authors: shen g. Clin Pharmacol Ther. 2024 Nov;116(5):1231-1239. doi: 10.1002/cpt.3337. Epub 2024 Jun 28. Clin Pharmacol Ther. 2024. PMID: 38940465 Clinical Trial.

2

Pharmacokinetics, Safety, and Tolerability of the Direct-acting Hepatitis C Antiviral Sofosbuvir in HealthyChineseSubjects.

Li X, Chen H, Niu J, Chen G, Shen G, Massetto B, Brainard DM, Zhu X, Zhang H, Ding Y. Li X, et al. Among authors: shen g. Clin Ther. 2018 Sep;40(9):1556-1566. doi: 10.1016/j.clinthera.2018.07.018. Epub 2018 Sep 2. Clin Ther. 2018. PMID: 30185395 Clinical Trial.

3

Pharmacokinetics, Safety, and Tolerability of Ledipasvir/Sofosbuvir and Sofosbuvir/Velpatasvir in Healthy Chinese Subjects.

Li C, Li X, Zhu X, Zhang H, Shen G, Kersey K, Ding Y. Li C, et al. Among authors: shen g. Clin Ther. 2020 Mar;42(3):448-457. doi: 10.1016/j.clinthera.2020.01.013. Epub 2020 Feb 27. Clin Ther. 2020. PMID: 32115243 Clinical Trial.

4

Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID-19, in Healthy Subjects.

Humeniuk R, Mathias A, Cao H, Osinusi A, Shen G, Chng E, Ling J, Vu A, German P. Humeniuk R, et al. Among authors: shen g. Clin Transl Sci. 2020 Sep;13(5):896-906. doi: 10.1111/cts.12840. Epub 2020 Aug 5. Clin Transl Sci. 2020. PMID: 32589775 Free PMC article. Clinical Trial.

5

Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist.

Younis I, Weber E, Nelson C, Kirby BJ, Shen G, Xiao D, Watkins TR, Othman AA. Younis I, et al. Among authors: shen g. Clin Pharmacokinet. 2023 Apr;62(4):609-621. doi: 10.1007/s40262-023-01214-w. Epub 2023 Mar 11. Clin Pharmacokinet. 2023. PMID: 36906733 Free PMC article.

6

Pharmacokinetics, Disposition, and Biotransformation of [¹⁴C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion.

Weber E, Subramanian R, Rowe W, Graupe M, Ling J, Shen G, Begley R, Sager J, Wolckenhauer S, Rhee M, Palaparthy R, Singh R. Weber E, et al. Among authors: shen g. Clin Pharmacokinet. 2024 Feb;63(2):241-253. doi: 10.1007/s40262-023-01328-1. Epub 2024 Jan 18. Clin Pharmacokinet. 2024. PMID: 38236562

7

Pharmacokinetics and Safety of Cilofexor and Firsocostat in Healthy Japanese and Non-Japanese Participants.

Younis IR, Nelson C, Weber EJ, Shen G, Qin AR, Xiao D, Watkins TR, Othman AA. Younis IR, et al. Among authors: shen g. J Clin Pharmacol. 2024 Dec;64(12):1586-1593. doi: 10.1002/jcph.6114. Epub 2024 Aug 30. J Clin Pharmacol. 2024. PMID: 39213138 Clinical Trial.

8

Clinical Pharmacokinetics and Safety of Remdesivir in Phase I Participants with Varying Degrees of Renal Impairment.

Zhang H, Humeniuk R, Regan S, Koullias Y, Davies S, John A, Shen G, Xiao D, Hyland RH, Winter H, Kim A. Zhang H, et al. Among authors: shen g. Clin Pharmacokinet. 2024 Nov 19. doi: 10.1007/s40262-024-01453-5. Online ahead of print. Clin Pharmacokinet. 2024. PMID: 39562399

9

Pharmacokinetics and safety of boosted elvitegravir in subjects with hepatic impairment.

Custodio JM, Rhee M, Shen G, Ling KH, Kearney BP, Ramanathan S. Custodio JM, et al. Among authors: shen g. Antimicrob Agents Chemother. 2014 May;58(5):2564-9. doi: 10.1128/AAC.02180-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550332 Free PMC article. Clinical Trial.

10

Safety, tolerability and immunogenicity of GS-4774, a hepatitis B virus-specific therapeutic vaccine, in healthy subjects: a randomized study.

Gaggar A, Coeshott C, Apelian D, Rodell T, Armstrong BR, Shen G, Subramanian GM, McHutchison JG. Gaggar A, et al. Among authors: shen g. Vaccine. 2014 Sep 3;32(39):4925-31. doi: 10.1016/j.vaccine.2014.07.027. Epub 2014 Jul 18. Vaccine. 2014. PMID: 25045824 Free article. Clinical Trial.

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