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759 results

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A metagenomic prospective cohort study on gut microbiome composition and clinical infection in small bowel transplantation.
Madhav A, Bousfield R, Pereira-Dias J, Cormie C, Forrest S, Keane J, Kermack L, Higginson E, Dougan G, Spiers H, Massey D, Sharkey L, Rutter C, Woodward J, Russell N, Amin I, Butler A, Atkinson K, Dymond T, Bartholdson Scott J, Baker S, Gkrania-Klotsas E. Madhav A, et al. Among authors: dougan g. Gut Microbes. 2024 Jan-Dec;16(1):2323232. doi: 10.1080/19490976.2024.2323232. Epub 2024 Mar 4. Gut Microbes. 2024. PMID: 38439546 Free PMC article.
Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia.
Navapurkar V, Bartholdson Scott J, Maes M, Hellyer TP, Higginson E, Forrest S, Pereira-Dias J, Parmar S, Heasman-Hunt E, Polgarova P, Brown J, Titti L, Smith WP, Scott J, Rostron A, Routledge M, Sapsford D, Török ME, McMullan R, Enoch DA, Wong V; VAP-Rapid investigators; Curran MD, Brown NM, Simpson AJ, Herre J, Dougan G, Conway Morris A. Navapurkar V, et al. Among authors: dougan g. Wellcome Open Res. 2022 Oct 12;6:256. doi: 10.12688/wellcomeopenres.17099.3. eCollection 2021. Wellcome Open Res. 2022. PMID: 36337362 Free PMC article.
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii.
Baker S, Krishna A, Higham S, Naydenova P, O'Leary S, Scott JB, Harcourt K, Forrest S, Goulding D, Thi Nguyen TN, Toan ND, Alekseeva E, Zhou Q, Andreozzi I, Sobotic B, Craig H, Wong V, Forrest-Owen N, Sanchez DM, Pearce C, Roberts L, Watson S, Clare S, Torok ME, Dougan G, Kellam P, Tregoning JS, Reece ST. Baker S, et al. Among authors: dougan g. Nat Commun. 2024 Sep 12;15(1):7979. doi: 10.1038/s41467-024-52357-8. Nat Commun. 2024. PMID: 39266557 Free PMC article.
Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor.
Perera MR, Greenwood EJD, Crozier TWM, Elder EG, Schmitt J, Crump CM, Lehner PJ, Wills MR, Sinclair JH; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research COVID BioResource Collaboration. Perera MR, et al. J Infect Dis. 2023 Feb 14;227(4):543-553. doi: 10.1093/infdis/jiac452. J Infect Dis. 2023. PMID: 36408607 Free PMC article.
Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study.
Dyson ZA, Ashton PM, Khanam F, Chunga Chirambo A, Shakya M, Meiring JE, Tonks S, Karkey A, Msefula C, Clemens JD, Dunstan SJ, Baker S, Dougan G, Pitzer VE, Basnyat B, Qadri F, Heyderman RS, Gordon MA, Pollard AJ, Holt KE; STRATAA Study Group. Dyson ZA, et al. Among authors: dougan g. Lancet Microbe. 2024 Aug;5(8):100841. doi: 10.1016/S2666-5247(24)00047-8. Epub 2024 Jul 9. Lancet Microbe. 2024. PMID: 38996496 Free PMC article.
EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC. Randzavola LO, et al. Among authors: dougan gj. Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387. Elife. 2022. PMID: 36421765 Free PMC article.
A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia.
Cuypers WL, Meysman P, Weill FX, Hendriksen RS, Beyene G, Wain J, Nair S, Chattaway MA, Perez-Sepulveda BM, Ceyssens PJ, de Block T, Lee WWY, Pardos de la Gandara M, Kornschober C, Moran-Gilad J, Veldman KT, Cormican M, Torpdahl M, Fields PI, Černý T, Hardy L, Tack B, Mellor KC, Thomson N, Dougan G, Deborggraeve S, Jacobs J, Laukens K, Van Puyvelde S. Cuypers WL, et al. Among authors: dougan g. Nat Commun. 2023 Jun 14;14(1):3517. doi: 10.1038/s41467-023-38902-x. Nat Commun. 2023. PMID: 37316492 Free PMC article. Review.
Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups.
Hurler L, Szilágyi Á, Mescia F, Bergamaschi L, Mező B, Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Würzner R; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Lyons PA, Toonen EJM, Prohászka Z. Hurler L, et al. Front Immunol. 2023 Mar 27;14:1162171. doi: 10.3389/fimmu.2023.1162171. eCollection 2023. Front Immunol. 2023. PMID: 37051252 Free PMC article.
759 results