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Page 1
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.
Krawczynska N, Wang Y, Lim K, Das Gupta A, Lenczowski A, Abughazaleh M, Bendre SV, Kockaya LI, Schane CP, Fei Y, Hernandez AG, Drnevich J, Chan J, Dobrucki LW, Boppart MD, Ostrander J, Nelson ER. Krawczynska N, et al. bioRxiv [Preprint]. 2024 Aug 2:2024.08.02.606061. doi: 10.1101/2024.08.02.606061. bioRxiv. 2024. PMID: 39131340 Free PMC article. Preprint.
Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells.
Vidana Gamage HE, Albright ST, Smith AJ, Farmer R, Shahoei SH, Wang Y, Fink EC, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Das Gupta A, Bendre SV, Nguyen T, Tiwari S, Krawczynska N, He S, Tjoanda E, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Apetoh L, Hergenrother PJ, Nelson ER. Vidana Gamage HE, et al. Among authors: krawczynska n. Cancer Lett. 2024 Aug 10;597:217086. doi: 10.1016/j.canlet.2024.217086. Epub 2024 Jun 27. Cancer Lett. 2024. PMID: 38944231 Free article.
NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors.
Vidana Gamage HE, Shahoei SH, Wang Y, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Das Gupta A, Bendre SV, Nguyen T, Tiwari S, Tjoanda E, Krawczynska N, He S, Albright ST, Farmer R, Smith AJ, Fink EC, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Hergenrother PJ, Apetoh L, Nelson ER. Vidana Gamage HE, et al. Among authors: krawczynska n. Cancer Lett. 2024 Aug 10;597:217042. doi: 10.1016/j.canlet.2024.217042. Epub 2024 Jun 20. Cancer Lett. 2024. PMID: 38908543 Free article.
Cholesterol Metabolite 27-Hydroxycholesterol Enhances the Secretion of Cancer Promoting Extracellular Vesicles by a Mitochondrial ROS-Induced Impairment of Lysosomal Function.
Das Gupta A, Park J, Sorrells JE, Kim H, Krawczynska N, Gamage HEV, Nelczyk AT, Boppart SA, Boppart MD, Nelson ER. Das Gupta A, et al. Among authors: krawczynska n. bioRxiv [Preprint]. 2024 May 1:2024.05.01.591500. doi: 10.1101/2024.05.01.591500. bioRxiv. 2024. PMID: 38746134 Free PMC article. Preprint.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. Welsh JA, et al. J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404. J Extracell Vesicles. 2024. PMID: 38326288 Free PMC article.
Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression.
Gamage HEV, Shahoei SH, Albright ST, Wang Y, Smith AJ, Farmer R, Fink EC, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Gupta AD, Bendre SV, Nguyen T, Tiwari S, Krawczynska N, He S, Tjoanda E, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Apetoh L, Hergenrother PJ, Nelson ER. Gamage HEV, et al. Among authors: krawczynska n. bioRxiv [Preprint]. 2023 Aug 14:2023.08.14.553229. doi: 10.1101/2023.08.14.553229. bioRxiv. 2023. PMID: 37645737 Free PMC article. Preprint.
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer.
Nelczyk AT, Ma L, Gupta AD, Gamage HEV, McHenry MT, Henn MA, Kadiri M, Wang Y, Krawczynska N, Bendre S, He S, Shahoei SH, Madak-Erdogan Z, Hsiao SH, Saleh T, Carpenter V, Gewirtz DA, Spinella MJ, Nelson ER. Nelczyk AT, et al. Among authors: krawczynska n. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166515. doi: 10.1016/j.bbadis.2022.166515. Epub 2022 Aug 4. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35932893 Free PMC article.
The Liver X Receptor Is Selectively Modulated to Differentially Alter Female Mammary Metastasis-associated Myeloid Cells.
Ma L, Vidana Gamage HE, Tiwari S, Han C, Henn MA, Krawczynska N, Dibaeinia P, Koelwyn GJ, Das Gupta A, Bautista Rivas RO, Wright CL, Xu F, Moore KJ, Sinha S, Nelson ER. Ma L, et al. Among authors: krawczynska n. Endocrinology. 2022 Jul 1;163(7):bqac072. doi: 10.1210/endocr/bqac072. Endocrinology. 2022. PMID: 35569056 Free PMC article.
22 results