Wai LK - Search Results

1

A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer.

Shamsudin NF, Leong SW, Koeberle A, Suriya U, Rungrotmongkol T, Chia SL, Taher M, Haris MS, Alshwyeh HA, Alosaimi AA, Mediani A, Ilowefah MA, Islami D, Mohd Faudzi SM, Fasihi Mohd Aluwi MF, Wai LK, Rullah K. Shamsudin NF, et al. Among authors: wai lk. Future Med Chem. 2024 Aug 2;16(15):1499-1517. doi: 10.1080/17568919.2024.2363668. Epub 2024 Jul 1. Future Med Chem. 2024. PMID: 38949858

2

Inhibition of prostaglandin E(2) production by synthetic minor prenylated chalcones and flavonoids: synthesis, biological activity, crystal structure, and in silico evaluation.

Rullah K, Mohd Aluwi MF, Yamin BM, Abdul Bahari MN, Wei LS, Ahmad S, Abas F, Ismail NH, Jantan I, Wai LK. Rullah K, et al. Among authors: wai lk. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3826-34. doi: 10.1016/j.bmcl.2014.06.061. Epub 2014 Jun 27. Bioorg Med Chem Lett. 2014. PMID: 25027933

3

In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids.

Mohd Faudzi SM, Leong SW, Auwal FA, Abas F, Wai LK, Ahmad S, Tham CL, Shaari K, Lajis NH, Yamin BM. Mohd Faudzi SM, et al. Among authors: wai lk. Arch Pharm (Weinheim). 2021 Jan;354(1):e2000161. doi: 10.1002/ardp.202000161. Epub 2020 Sep 4. Arch Pharm (Weinheim). 2021. PMID: 32886410

4

Oestrogenic activity of mimosine on MCF-7 breast cancer cell line through the ERα-mediated pathway.

Huq AM, Wai LK, Rullah K, Mohd Aluwi MFF, Stanslas J, Jamal JA. Huq AM, et al. Among authors: wai lk. Chem Biol Drug Des. 2019 Mar;93(3):222-231. doi: 10.1111/cbdd.13404. Epub 2018 Oct 21. Chem Biol Drug Des. 2019. PMID: 30251480

5

Probing the effects of fish oil on the delivery and inflammation-inducing potential of imiquimod.

Rehman K, Aluwi MF, Rullah K, Wai LK, Mohd Amin MC, Zulfakar MH. Rehman K, et al. Among authors: wai lk. Int J Pharm. 2015 Jul 25;490(1-2):131-41. doi: 10.1016/j.ijpharm.2015.05.045. Epub 2015 May 21. Int J Pharm. 2015. PMID: 26003416

6

Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents.

Leong SW, Faudzi SM, Abas F, Aluwi MF, Rullah K, Wai LK, Bahari MN, Ahmad S, Tham CL, Shaari K, Lajis NH. Leong SW, et al. Among authors: wai lk. Molecules. 2014 Oct 9;19(10):16058-81. doi: 10.3390/molecules191016058. Molecules. 2014. PMID: 25302700 Free PMC article.

7

G-quadruplex ligands as therapeutic agents against cancer, neurological disorders and viral infections.

Yan MP, Wee CE, Yen KP, Stevens A, Wai LK. Yan MP, et al. Among authors: wai lk. Future Med Chem. 2023 Nov;15(21):1987-2009. doi: 10.4155/fmc-2023-0202. Epub 2023 Nov 7. Future Med Chem. 2023. PMID: 37933551 Review.

8

Synthesis and effects of pyrazolines and isoxazoles on the phagocytic chemotaxis and release of reactive oxygen species by zymosan stimulated human neutrophils.

Bukhari SN, Jantan I, Wai LK, Lajis NH, Abbas F, Jasamai M. Bukhari SN, et al. Among authors: wai lk. Med Chem. 2013 Dec;9(8):1091-8. doi: 10.2174/1573406411309080011. Med Chem. 2013. PMID: 23092331

9

Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase.

Shaari K, Suppaiah V, Wai LK, Stanslas J, Tejo BA, Israf DA, Abas F, Ismail IS, Shuaib NH, Zareen S, Lajis NH. Shaari K, et al. Among authors: wai lk. Bioorg Med Chem. 2011 Nov 1;19(21):6340-7. doi: 10.1016/j.bmc.2011.09.001. Epub 2011 Sep 10. Bioorg Med Chem. 2011. PMID: 21958738

10

The impact of cycleanine in cancer research: a computational study.

Nwaefulu ON, Al-Shar'i NA, Owolabi JO, Sagineedu SR, Woei LC, Wai LK, Islam MK, Jayanthi S, Stanslas J. Nwaefulu ON, et al. Among authors: wai lk. J Mol Model. 2022 Oct 4;28(11):340. doi: 10.1007/s00894-022-05326-1. J Mol Model. 2022. PMID: 36194315

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