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Ruthenium complex containing 1,3-thiazolidine-2-thione inhibits hepatic cancer stem cells by suppressing Akt/mTOR signalling and leading to apoptotic and autophagic cell death.
Neves SP, Bomfim LM, Kataura T, Carvalho SG, Nogueira ML, Dias RB, Valverde LF, Gurgel Rocha CA, Soares MBP, Silva MMD, Batista AA, Korolchuk VI, Bezerra DP. Neves SP, et al. Biomed Pharmacother. 2024 Aug;177:117059. doi: 10.1016/j.biopha.2024.117059. Epub 2024 Jul 1. Biomed Pharmacother. 2024. PMID: 38955086 Free article.
Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells.
Rodrigues ACBDC, Bomfim LM, Neves SP, Soares MBP, Dias RB, Valverde LF, Rocha CAG, Costa EV, da Silva FMA, Rocha WC, Koolen HHF, Bezerra DP. Rodrigues ACBDC, et al. Among authors: neves sp. Biomed Pharmacother. 2021 Oct;142:112034. doi: 10.1016/j.biopha.2021.112034. Epub 2021 Aug 16. Biomed Pharmacother. 2021. PMID: 34411914 Free article.
A novel ruthenium complex with xanthoxylin induces S-phase arrest and causes ERK1/2-mediated apoptosis in HepG2 cells through a p53-independent pathway.
de Carvalho NC, Neves SP, Dias RB, Valverde LF, Sales CBS, Rocha CAG, Soares MBP, Dos Santos ER, Oliveira RMM, Carlos RM, Nogueira PCL, Bezerra DP. de Carvalho NC, et al. Among authors: neves sp. Cell Death Dis. 2018 Jan 23;9(2):79. doi: 10.1038/s41419-017-0104-6. Cell Death Dis. 2018. PMID: 29362398 Free PMC article.
Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination.
das Neves SP, Delivanoglou N, Ren Y, Cucuzza CS, Makuch M, Almeida F, Sanchez G, Barber MJ, Rego S, Schrader R, Faroqi AH, Thomas JL, McLean PJ, Oliveira TG, Irani SR, Piehl F, Da Mesquita S. das Neves SP, et al. Immunity. 2024 Oct 8;57(10):2328-2343.e8. doi: 10.1016/j.immuni.2024.08.004. Epub 2024 Aug 31. Immunity. 2024. PMID: 39217987
Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion.
Udine E, DeJesus-Hernandez M, Tian S, das Neves SP, Crook R, Finch NA, Baker MC, Pottier C, Graff-Radford NR, Boeve BF, Petersen RC, Knopman DS, Josephs KA, Oskarsson B, Da Mesquita S, Petrucelli L, Gendron TF, Dickson DW, Rademakers R, van Blitterswijk M. Udine E, et al. Among authors: das neves sp. Acta Neuropathol. 2024 Apr 19;147(1):73. doi: 10.1007/s00401-024-02720-2. Acta Neuropathol. 2024. PMID: 38641715 Free PMC article.
32 results