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Page 1
Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.
Spanjaard A, Shah R, de Groot D, Buoninfante OA, Morris B, Lieftink C, Pritchard C, Zürcher LM, Ormel S, Catsman JJI, de Korte-Grimmerink R, Siteur B, Proost N, Boadum T, van de Ven M, Song JY, Kreft M, van den Berk PCM, Beijersbergen RL, Jacobs H. Spanjaard A, et al. Among authors: de korte grimmerink r, de groot d. Nucleic Acids Res. 2022 Jul 22;50(13):7420-7435. doi: 10.1093/nar/gkac545. Nucleic Acids Res. 2022. PMID: 35819193 Free PMC article.
Mammalian life depends on two distinct pathways of DNA damage tolerance.
Buoninfante OA, Pilzecker B, Spanjaard A, de Groot D, Prekovic S, Song JY, Lieftink C, Ayidah M, Pritchard CEJ, Vivié J, Mcgrath KE, Huijbers IJ, Philipsen S, von Lindern M, Zwart W, Beijersbergen RL, Palis J, van den Berk PCM, Jacobs H. Buoninfante OA, et al. Among authors: de groot d. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216055120. doi: 10.1073/pnas.2216055120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669105 Free PMC article.
Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.
Spanjaard A, Stratigopoulou M, de Groot D, Aslam M, van den Berk PCM, Stappenbelt C, Ayidah M, Catsman JJI, Pardieck IN, Kreft M, Arens R, Guikema JEJ, Jacobs H. Spanjaard A, et al. Among authors: de groot d. Front Immunol. 2023 Jan 9;13:986863. doi: 10.3389/fimmu.2022.986863. eCollection 2022. Front Immunol. 2023. PMID: 36700204 Free PMC article.
ADARp150 counteracts whole genome duplication.
van Gemert F, Drakaki A, Lozano IM, de Groot D, Uiterkamp MS, Proost N, Lieftink C, van de Ven M, Beijersbergen RL, Jacobs H, Te Riele H. van Gemert F, et al. Among authors: de groot d. Nucleic Acids Res. 2024 Sep 23;52(17):10370-10384. doi: 10.1093/nar/gkae700. Nucleic Acids Res. 2024. PMID: 39189458 Free PMC article.
CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors.
Lei X, de Groot DC, Welters MJP, de Wit T, Schrama E, van Eenennaam H, Santegoets SJ, Oosenbrug T, van der Veen A, Vos JL, Zuur CL, de Miranda NFCC, Jacobs H, van der Burg SH, Borst J, Xiao Y. Lei X, et al. Cell Mol Immunol. 2024 Apr;21(4):374-392. doi: 10.1038/s41423-024-01133-1. Epub 2024 Feb 21. Cell Mol Immunol. 2024. PMID: 38383773 Free PMC article.
Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma.
Ramirez CFA, Taranto D, Ando-Kuri M, de Groot MHP, Tsouri E, Huang Z, de Groot D, Kluin RJC, Kloosterman DJ, Verheij J, Xu J, Vegna S, Akkari L. Ramirez CFA, et al. Among authors: de groot mhp, de groot d. Nat Commun. 2024 Mar 22;15(1):2581. doi: 10.1038/s41467-024-46835-2. Nat Commun. 2024. PMID: 38519484 Free PMC article.
ENA Clinical Practice Guideline Synopsis: Alternatives to Opioids.
MacPherson-Dias R, Slifko A, Gibson J, Slivinski A, Camarda A, Coffey S, DeGroot D, Dixon C, Kaiser J, Perry A, Tucker A, Wachtel S, Bishop-Royse J, Delao AM. MacPherson-Dias R, et al. J Emerg Nurs. 2024 Nov;50(6):749-761. doi: 10.1016/j.jen.2024.08.008. J Emerg Nurs. 2024. PMID: 39537263 No abstract available.
Molecular imaging supports the development of multispecific cancer antibodies.
van Winkel CAJ, Pierik FR, Brouwers AH, de Groot DJA, de Vries EGE, Lub-de Hooge MN. van Winkel CAJ, et al. Among authors: de groot dja. Nat Rev Clin Oncol. 2024 Dec;21(12):852-866. doi: 10.1038/s41571-024-00946-3. Epub 2024 Sep 26. Nat Rev Clin Oncol. 2024. PMID: 39327536 Review.
209 results