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The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.
Knoll R, Helbig ET, Dahm K, Bolaji O, Hamm F, Dietrich O, van Uelft M, Müller S, Bonaguro L, Schulte-Schrepping J, Petrov L, Krämer B, Kraut M, Stubbemann P, Thibeault C, Brumhard S, Theis H, Hack G, De Domenico E, Nattermann J, Becker M, Beyer MD, Hillus D, Georg P, Loers C, Tiedemann J, Tober-Lau P, Lippert L, Millet Pascual-Leone B, Tacke F, Rohde G, Suttorp N, Witzenrath M; CAPNETZ Study Group; Pa-COVID-19 Study Group; Saliba AE, Ulas T, Polansky JK, Sawitzki B, Sander LE, Schultze JL, Aschenbrenner AC, Kurth F. Knoll R, et al. Among authors: becker m. Cell. 2024 Aug 8;187(16):4318-4335.e20. doi: 10.1016/j.cell.2024.06.014. Epub 2024 Jul 3. Cell. 2024. PMID: 38964327 Free article.
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.
Kapellos TS, Baßler K, Fujii W, Nalkurthi C, Schaar AC, Bonaguro L, Pecht T, Galvao I, Agrawal S, Saglam A, Dudkin E, Frishberg A, de Domenico E, Horne A, Donovan C, Kim RY, Gallego-Ortega D, Gillett TE, Ansari M, Schulte-Schrepping J, Offermann N, Antignano I, Sivri B, Lu W, Eapen MS, van Uelft M, Osei-Sarpong C, van den Berge M, Donker HC, Groen HJM, Sohal SS, Klein J, Schreiber T, Feißt A, Yildirim AÖ, Schiller HB, Nawijn MC, Becker M, Händler K, Beyer M, Capasso M, Ulas T, Hasenauer J, Pizarro C, Theis FJ, Hansbro PM, Skowasch D, Schultze JL. Kapellos TS, et al. Among authors: becker m. Cell Rep. 2023 Jun 27;42(6):112525. doi: 10.1016/j.celrep.2023.112525. Epub 2023 May 26. Cell Rep. 2023. PMID: 37243592 Free PMC article.
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll R, Bonaguro L, Dos Santos JC, Warnat-Herresthal S, Jacobs-Cleophas MCP, Blümel E, Reusch N, Horne A, Herbert M, Nuesch-Germano M, Otten T, van der Heijden WA, van de Wijer L, Shalek AK, Händler K, Becker M, Beyer MD, Netea MG, Joosten LAB, van der Ven AJAM, Schultze JL, Aschenbrenner AC. Knoll R, et al. Among authors: becker m. Front Immunol. 2023 Nov 20;14:1275136. doi: 10.3389/fimmu.2023.1275136. eCollection 2023. Front Immunol. 2023. PMID: 38077315 Free PMC article.
A Bioinformatic Toolkit for Single-Cell mRNA Analysis.
Baßler K, Günther P, Schulte-Schrepping J, Becker M, Biernat P. Baßler K, et al. Among authors: becker m. Methods Mol Biol. 2019;1979:433-455. doi: 10.1007/978-1-4939-9240-9_26. Methods Mol Biol. 2019. PMID: 31028653
Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.
Warnat-Herresthal S, Perrakis K, Taschler B, Becker M, Baßler K, Beyer M, Günther P, Schulte-Schrepping J, Seep L, Klee K, Ulas T, Haferlach T, Mukherjee S, Schultze JL. Warnat-Herresthal S, et al. Among authors: becker m. iScience. 2020 Jan 24;23(1):100780. doi: 10.1016/j.isci.2019.100780. Epub 2019 Dec 18. iScience. 2020. PMID: 31918046 Free PMC article.
A novel computational architecture for large-scale genomics.
Becker M, Schultze H, Bresniker K, Singhal S, Ulas T, Schultze JL. Becker M, et al. Nat Biotechnol. 2020 Nov;38(11):1239-1241. doi: 10.1038/s41587-020-0699-5. Nat Biotechnol. 2020. PMID: 32999473 No abstract available.
Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal S, Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Händler K, Pickkers P, Aziz NA, Ktena S, Tran F, Bitzer M, Ossowski S, Casadei N, Herr C, Petersheim D, Behrends U, Kern F, Fehlmann T, Schommers P, Lehmann C, Augustin M, Rybniker J, Altmüller J, Mishra N, Bernardes JP, Krämer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Siever C, Kraut M, Desai M, Monnet B, Saridaki M, Siegel CM, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Schreiber S, Kim-Hellmuth S; COVID-19 Aachen Study (COVAS); Nattermann J, Skowasch D, Kurth I, Keller A, Bals R, Nürnberg P, Rieß O, Rosenstiel P, Netea MG, Theis F, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T; Deutsche COVID-19 Omics Initiative (DeCOI); Breteler MMB, Giamarellos-Bourboulis EJ, Kox M, Becker M, Cheran S, Woodacre MS, Goh EL, Schultze JL. Warnat-Herresthal S, et al. Among authors: becker m. Nature. 2021 Jun;594(7862):265-270. doi: 10.1038/s41586-021-03583-3. Epub 2021 May 26. Nature. 2021. PMID: 34040261 Free PMC article.
Privacy considerations for sharing genomics data.
Oestreich M, Chen D, Schultze JL, Fritz M, Becker M. Oestreich M, et al. Among authors: becker m. EXCLI J. 2021 Jul 16;20:1243-1260. doi: 10.17179/excli2021-4002. eCollection 2021. EXCLI J. 2021. PMID: 34345236 Free PMC article. Review.
Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs.
Langkabel J, Horne A, Bonaguro L, Holsten L, Hesse T, Knaus A, Riedel Y, Becker M, Händler K, Elmzzahi T, Bassler K, Reusch N, Yeghiazarian LH, Pecht T, Saglam A, Ulas T, Aschenbrenner AC, Kaiser F, Kubaczka C, Schultze JL, Schorle H. Langkabel J, et al. Among authors: becker m. Nat Commun. 2021 Dec 16;12(1):7322. doi: 10.1038/s41467-021-27586-w. Nat Commun. 2021. PMID: 34916498 Free PMC article.
4,076 results