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Page 1
Lineage plasticity in cancer: a shared pathway of therapeutic resistance.
Quintanal-Villalonga Á, Chan JM, Yu HA, Pe'er D, Sawyers CL, Sen T, Rudin CM. Quintanal-Villalonga Á, et al. Among authors: sen t. Nat Rev Clin Oncol. 2020 Jun;17(6):360-371. doi: 10.1038/s41571-020-0340-z. Epub 2020 Mar 9. Nat Rev Clin Oncol. 2020. PMID: 32152485 Free PMC article. Review.
Targeted Therapies and Biomarkers in Small Cell Lung Cancer.
Taniguchi H, Sen T, Rudin CM. Taniguchi H, et al. Among authors: sen t. Front Oncol. 2020 May 20;10:741. doi: 10.3389/fonc.2020.00741. eCollection 2020. Front Oncol. 2020. PMID: 32509576 Free PMC article. Review.
ATR inhibition activates cancer cell cGAS/STING-interferon signaling and promotes antitumor immunity in small-cell lung cancer.
Taniguchi H, Chakraborty S, Takahashi N, Banerjee A, Caeser R, Zhan YA, Tischfield SE, Chow A, Nguyen EM, Villalonga ÁQ, Manoj P, Shah NS, Rosario S, Hayatt O, Qu R, de Stanchina E, Chan J, Mukae H, Thomas A, Rudin CM, Sen T. Taniguchi H, et al. Among authors: sen t. Sci Adv. 2024 Sep 27;10(39):eado4618. doi: 10.1126/sciadv.ado4618. Epub 2024 Sep 27. Sci Adv. 2024. PMID: 39331709 Free PMC article.
Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies.
Cardnell RJ, Li L, Sen T, Bara R, Tong P, Fujimoto J, Ireland AS, Guthrie MR, Bheddah S, Banerjee U, Kalu NN, Fan YH, Dylla SJ, Johnson FM, Wistuba II, Oliver TG, Heymach JV, Glisson BS, Wang J, Byers LA. Cardnell RJ, et al. Among authors: sen t. Oncotarget. 2017 Sep 1;8(43):73419-73432. doi: 10.18632/oncotarget.20621. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088717 Free PMC article.
MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.
Dammert MA, Brägelmann J, Olsen RR, Böhm S, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretić L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Büttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, Sos ML. Dammert MA, et al. Among authors: sen t. Nat Commun. 2019 Aug 2;10(1):3485. doi: 10.1038/s41467-019-11371-x. Nat Commun. 2019. PMID: 31375684 Free PMC article.
Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts.
Caeser R, Egger JV, Chavan S, Socci ND, Jones CB, Kombak FE, Asher M, Roehrl MH, Shah NS, Allaj V, Manoj P, Tischfield SE, Kulick A, Meneses M, Iacobuzio-Donahue CA, Lai WV, Bhanot U, Baine MK, Rekhtman N, Hollmann TJ, de Stanchina E, Poirier JT, Rudin CM, Sen T. Caeser R, et al. Among authors: sen t. Nat Commun. 2022 Apr 19;13(1):2144. doi: 10.1038/s41467-022-29794-4. Nat Commun. 2022. PMID: 35440124 Free PMC article.
505 results