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Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease.
Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schroeder KR, Valenti AM, Harrison FE, Hasty AH. Robertson KV, et al. Among authors: shrestha s. Res Sq [Preprint]. 2024 Jun 27:rs.3.rs-4559940. doi: 10.21203/rs.3.rs-4559940/v1. Res Sq. 2024. Update in: J Neuroinflammation. 2024 Sep 27;21(1):238. doi: 10.1186/s12974-024-03238-w PMID: 38978579 Free PMC article. Updated. Preprint.
The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler JP, Sampson L, Magnuson MA, Jacobson DA. Nakhe AY, et al. Among authors: shrestha s. bioRxiv [Preprint]. 2024 Feb 27:2023.06.20.545631. doi: 10.1101/2023.06.20.545631. bioRxiv. 2024. Update in: Elife. 2024 May 03;12:RP89967. doi: 10.7554/eLife.89967 PMID: 37546831 Free PMC article. Updated. Preprint.
Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease.
Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schleh MW, Schroeder KR, Valenti AM, Kramer AT, Harrison FE, Hasty AH. Robertson KV, et al. Among authors: shrestha s. J Neuroinflammation. 2024 Sep 27;21(1):238. doi: 10.1186/s12974-024-03238-w. J Neuroinflammation. 2024. PMID: 39334471 Free PMC article.
E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic β cells.
Oguh AU, Haemmerle MW, Sen S, Rozo AV, Shrestha S, Cartailler JP, Fazelinia H, Ding H, Preza S, Yang J, Yang X, Sussel L, Alvarez-Dominguez JR, Doliba N, Spruce LA, Arrojo E Drigo R, Stoffers DA. Oguh AU, et al. Among authors: shrestha s. Genes Dev. 2024 Dec 30. doi: 10.1101/gad.352010.124. Online ahead of print. Genes Dev. 2024. PMID: 39797759
3,409 results