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Page 1
Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing.
Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross OA, Murray ME, Faura J, Haggarty SJ, van Rooij JG, Mol MO, Hsiung GR, Graff C, Öijerstedt L, Neumann M, Asmann Y, McDonnell SK, Baheti S, Josephs KA, Whitwell JL, Bieniek KF, Forsberg L, Heuer H, Lago AL, Geier EG, Yokoyama JS, Oddi AP, Flanagan M, Mao Q, Hodges JR, Kwok JB, Domoto-Reilly K, Synofzik M, Wilke C, Onyike C, Dickerson BC, Evers BM, Dugger BN, Munoz DG, Keith J, Zinman L, Rogaeva E, Suh E, Gefen T, Geula C, Weintraub S, Diehl-Schmid J, Farlow MR, Edbauer D, Woodruff BK, Caselli RJ, Donker Kaat LL, Huey ED, Reiman EM, Mead S, King A, Roeber S, Nana AL, Ertekin-Taner N, Knopman DS, Petersen RC, Petrucelli L, Uitti RJ, Wszolek ZK, Ramos EM, Grinberg LT, Gorno Tempini ML, Rosen HJ, Spina S, Piguet O, Grossman M, Trojanowski JQ, Keene DC, Lee-Way J, Prudlo J, Geschwind DH, Rissman RA, Cruchaga C, Ghetti B, Halliday GM, Beach TG, Serrano GE, Arzberger T, Herms J, Boxer AL, Honig LS, Vonsattel JP, Lopez OL, Kofler J, White CL, Gearing M, Glass J, Rohrer JD, Irwin DJ, Lee EB, Van Deerlin V, Castellani R, Mesulam MM, Tartaglia MC, Finger EC… See abstract for full author list ➔ Pottier C, et al. Among authors: rissman ra. medRxiv [Preprint]. 2024 Jun 25:2024.06.24.24309088. doi: 10.1101/2024.06.24.24309088. medRxiv. 2024. PMID: 38978643 Free PMC article. Preprint.
Multi-omics Characterization of Epigenetic and Genetic Risk of Alzheimer Disease in Autopsied Brains from two Ethnic Groups.
Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN. Ma Y, et al. Among authors: rissman ra. medRxiv [Preprint]. 2024 Feb 14:2024.02.12.24302533. doi: 10.1101/2024.02.12.24302533. medRxiv. 2024. Update in: Acta Neuropathol. 2024 Aug 23;148(1):27. doi: 10.1007/s00401-024-02778-y PMID: 38405911 Free PMC article. Updated. Preprint.
A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with Early Alzheimer's Disease.
Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas R, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. Galasko D, et al. Among authors: rissman ra. medRxiv [Preprint]. 2024 Mar 22:2024.03.20.24304638. doi: 10.1101/2024.03.20.24304638. medRxiv. 2024. Update in: Alzheimers Res Ther. 2024 Jul 5;16(1):151. doi: 10.1186/s13195-024-01490-z PMID: 38562783 Free PMC article. Updated. Preprint.
Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups.
Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN. Ma Y, et al. Among authors: rissman ra. Acta Neuropathol. 2024 Aug 23;148(1):27. doi: 10.1007/s00401-024-02778-y. Acta Neuropathol. 2024. PMID: 39177846 Free PMC article.
Guidelines for the standardization of pre-analytical variables for salivary biomarker studies in Alzheimer's disease research: An updated review and consensus of the Salivary Biomarkers for Dementia Research Working Group.
Ng TKS, Udeh-Momoh C, Lim MA, Gleerup HS, Leifert W, Ajalo C, Ashton N, Zetterberg H, Rissman RA, Winston CN, O' Bryant S, Jenkins R, Carro E, Orive G, Tamburin S, Olvera-Rojas M, Solis-Urra P, Esteban-Cornejo I, Santos GAAD, Rajan KB, Koh D, Simonsen AH, Slowey PD; Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment: Biofluid Based Biomarkers Professional Interest Area Salivary Biomarkers for Dementia Research Working Group (ISTAART‐BBB‐PIA‐SWG). Ng TKS, et al. Among authors: rissman ra. Alzheimers Dement. 2024 Dec 30. doi: 10.1002/alz.14420. Online ahead of print. Alzheimers Dement. 2024. PMID: 39737743 Review.
Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease.
Grill JD, Tam S, Thai G, Vides B, Pierce AL, Green K, Gillen DL, Teng E, Kremen S, Beigi M, Rissman RA, Léger GC, Balasubramanian A, Revta C, Morrison R, Jennings R, Pa J, Zhang J, Jin S, Messer K, Feldman HH. Grill JD, et al. Among authors: rissman ra. Neurology. 2025 Jan 14;104(1):e210152. doi: 10.1212/WNL.0000000000210152. Epub 2024 Dec 13. Neurology. 2025. PMID: 39671543 Clinical Trial.
Clinical and neuropathological analysis of Down syndrome over 7 decades of life.
Sukreet S, Goodwill VS, Ngolab J, Kim HY, Leisher S, Salehi S, Rafii MS, Hiniker A, Rissman RA. Sukreet S, et al. Among authors: rissman ra. J Neuropathol Exp Neurol. 2024 Oct 29:nlae110. doi: 10.1093/jnen/nlae110. Online ahead of print. J Neuropathol Exp Neurol. 2024. PMID: 39471466 No abstract available.
Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis.
Avalos B, Kulbe JR, Ford MK, Laird AE, Walter K, Mante M, Florio JB, Boustani A, Chaillon A, Schlachetzki JCM, Sundermann EE, Volsky DJ, Rissman RA, Ellis RJ, Letendre SL, Iudicello J, Fields JA. Avalos B, et al. Among authors: rissman ra. Viruses. 2024 Sep 24;16(10):1509. doi: 10.3390/v16101509. Viruses. 2024. PMID: 39459844 Free PMC article.
The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer's Disease Trials.
Walter S, Langford O, Jimenez-Maggiora GA, Abdel-Latif S, Rissman RA, Grill JD, Karlawish J, Atri A, Bruschi S, Hussen K, Donohue MC, Marshall GA, Jicha G, Racke M, Turner RS, van Dyck CH, Venkatesh V, Yarasheski KE, Sperling R, Cummings J, Aisen PS, Raman R. Walter S, et al. Among authors: rissman ra. J Prev Alzheimers Dis. 2024;11(5):1435-1444. doi: 10.14283/jpad.2024.101. J Prev Alzheimers Dis. 2024. PMID: 39350391 Free PMC article.
220 results