Li T - Search Results

1

Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia.

Baghel MS, Burns GD, Tsapatsis M, Mallika AP, Cruz ALF, Cao T, Chen XK, Rosa I, Marx SR, Ye Y, Sun S, Li T, Wong PC. Baghel MS, et al. Among authors: li t. bioRxiv [Preprint]. 2024 Jun 29:2024.06.26.600814. doi: 10.1101/2024.06.26.600814. bioRxiv. 2024. PMID: 38979270 Free PMC article. Preprint.

2

APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.

Ma G, Li T, Price DL, Wong PC. Ma G, et al. Among authors: li t. J Neurosci. 2005 Jan 5;25(1):192-8. doi: 10.1523/JNEUROSCI.3814-04.2005. J Neurosci. 2005. PMID: 15634781 Free PMC article.

3

The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.

Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. Li T, et al. Nat Commun. 2016 Jul 4;7:12082. doi: 10.1038/ncomms12082. Nat Commun. 2016. PMID: 27373369 Free PMC article.

4

D-Glucose uptake and clearance in the tauopathy Alzheimer's disease mouse brain detected by on-resonance variable delay multiple pulse MRI.

Chen L, Wei Z, Chan KW, Li Y, Suchal K, Bi S, Huang J, Xu X, Wong PC, Lu H, van Zijl PC, Li T, Xu J. Chen L, et al. Among authors: li t, li y. J Cereb Blood Flow Metab. 2021 May;41(5):1013-1025. doi: 10.1177/0271678X20941264. Epub 2020 Jul 16. J Cereb Blood Flow Metab. 2021. PMID: 32669023 Free PMC article.

5

Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging.

Chen L, van Zijl PCM, Wei Z, Lu H, Duan W, Wong PC, Li T, Xu J. Chen L, et al. Among authors: li t. Neuroimage. 2021 Aug 1;236:118071. doi: 10.1016/j.neuroimage.2021.118071. Epub 2021 Apr 18. Neuroimage. 2021. PMID: 33878375 Free PMC article.

6

Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study.

Wei Z, Xu J, Chen L, Hirschler L, Barbier EL, Li T, Wong PC, Lu H. Wei Z, et al. Among authors: li t. NMR Biomed. 2021 Sep;34(9):e4568. doi: 10.1002/nbm.4568. Epub 2021 May 29. NMR Biomed. 2021. PMID: 34050996 Free PMC article.

7

[No title available]

[No authors listed] [No authors listed] PMID: 39751017

8

Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.

Li T, Ma G, Cai H, Price DL, Wong PC. Li T, et al. J Neurosci. 2003 Apr 15;23(8):3272-7. doi: 10.1523/JNEUROSCI.23-08-03272.2003. J Neurosci. 2003. PMID: 12716934 Free PMC article.

9

Binding sites of gamma-secretase inhibitors in rodent brain: distribution, postnatal development, and effect of deafferentation.

Yan XX, Li T, Rominger CM, Prakash SR, Wong PC, Olson RE, Zaczek R, Li YW. Yan XX, et al. Among authors: li t, li yw. J Neurosci. 2004 Mar 24;24(12):2942-52. doi: 10.1523/JNEUROSCI.0092-04.2004. J Neurosci. 2004. PMID: 15044533 Free PMC article.

10

Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin).

Choi SH, Leight SN, Lee VM, Li T, Wong PC, Johnson JA, Saraiva MJ, Sisodia SS. Choi SH, et al. Among authors: li t. J Neurosci. 2007 Jun 27;27(26):7006-10. doi: 10.1523/JNEUROSCI.1919-07.2007. J Neurosci. 2007. PMID: 17596449 Free PMC article.

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