Safar JG - Search Results

1

Neuropathologically-directed profiling of PRNP somatic and germline variants in sporadic human prion disease.

McDonough GA, Cheng Y, Morillo K, Doan RN, Kenny CJ, Foutz A, Kim C, Cohen ML, Appleby BS, Walsh CA, Safar JG, Huang AY, Miller MB. McDonough GA, et al. Among authors: safar jg. bioRxiv [Preprint]. 2024 Jun 29:2024.06.25.600668. doi: 10.1101/2024.06.25.600668. bioRxiv. 2024. Update in: Acta Neuropathol. 2024 Jul 24;148(1):10. doi: 10.1007/s00401-024-02774-2 PMID: 38979287 Free PMC article. Updated. Preprint.

2

Genome-wide association studies identify novel loci in rapidly progressive Alzheimer's disease.

Wang P, Lynn A, Miskimen K, Song YE, Wisniewski T, Cohen M, Appleby BS, Safar JG, Haines JL. Wang P, et al. Among authors: safar jg. Alzheimers Dement. 2024 Mar;20(3):2034-2046. doi: 10.1002/alz.13655. Epub 2024 Jan 7. Alzheimers Dement. 2024. PMID: 38184787 Free PMC article.

3

Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases.

Zhang W, Orrú CD, Foutz A, Ding M, Yuan J, Shah SZA, Zhang J, Kotobelli K, Gerasimenko M, Gilliland T, Chen W, Tang M, Cohen M, Safar J, Xu B, Hong DJ, Cui L, Hughson AG, Schonberger LB, Tatsuoka C, Chen SG, Greenlee JJ, Wang Z, Appleby BS, Caughey B, Zou WQ. Zhang W, et al. Acta Neuropathol. 2024 Jan 17;147(1):17. doi: 10.1007/s00401-023-02661-2. Acta Neuropathol. 2024. PMID: 38231266

4

Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease.

McDonough GA, Cheng Y, Morillo KS, Doan RN, Zhou Z, Kenny CJ, Foutz A, Kim C, Cohen ML, Appleby BS, Walsh CA, Safar JG, Huang AY, Miller MB. McDonough GA, et al. Among authors: safar jg. Acta Neuropathol. 2024 Jul 24;148(1):10. doi: 10.1007/s00401-024-02774-2. Acta Neuropathol. 2024. PMID: 39048735

5

[No title available]

[No authors listed] [No authors listed] PMID: 39750830

6

Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay.

Baranová S, Moško T, Brůžová M, Haldiman T, Kim C, Safar JG, Matěj R, Holada K. Baranová S, et al. Among authors: safar jg. Sci Rep. 2024 Mar 15;14(1):6294. doi: 10.1038/s41598-024-56789-6. Sci Rep. 2024. PMID: 38491063 Free PMC article.

7

The effect of Aβ seeding is dependent on the presence of knock-in genes in the App ^NL-G-F mice.

Lacoursiere SG, Safar J, Westaway D, Mohajerani MH, Sutherland RJ. Lacoursiere SG, et al. Front Dement. 2022 Sep 12;1:941879. doi: 10.3389/frdem.2022.941879. eCollection 2022. Front Dement. 2022. PMID: 39081481 Free PMC article.

8

Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer's disease tau.

Hromadkova L, Kim C, Haldiman T, Peng L, Zhu X, Cohen M, de Silva R, Safar JG. Hromadkova L, et al. Among authors: safar jg. Cell Biosci. 2023 Sep 18;13(1):174. doi: 10.1186/s13578-023-01133-0. Cell Biosci. 2023. PMID: 37723591 Free PMC article.

9

Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer's Disease and Related Dementias.

Hromadkova L, Siddiqi MK, Liu H, Safar JG. Hromadkova L, et al. Among authors: safar jg. Cells. 2022 Sep 26;11(19):2997. doi: 10.3390/cells11192997. Cells. 2022. PMID: 36230957 Free PMC article. Review.

10

Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer's disease.

Kim C, Haldiman T, Kang SG, Hromadkova L, Han ZZ, Chen W, Lissemore F, Lerner A, de Silva R, Cohen ML, Westaway D, Safar JG. Kim C, et al. Among authors: safar jg. Sci Transl Med. 2022 Jan 5;14(626):eabg0253. doi: 10.1126/scitranslmed.abg0253. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985969 Free PMC article.

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