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Page 1
Transcriptional Phenocopies of Deleterious KEAP1 Mutations Correlate with Survival Outcomes in Lung Cancer Treated with Immunotherapy.
Scalera S, Ricciuti B, Marinelli D, Mazzotta M, Cipriani L, Bon G, Schiavoni G, Terrenato I, Di Federico A, Alessi JV, Fanciulli M, Ciuffreda L, De Nicola F, Goeman F, Caravagna G, Santini D, De Maria R, Cappuzzo F, Ciliberto G, Jamal-Hanjani M, Awad MM, McGranahan N, Maugeri-Saccà M. Scalera S, et al. Among authors: fanciulli m. Clin Cancer Res. 2024 Oct 1;30(19):4397-4411. doi: 10.1158/1078-0432.CCR-24-0626. Clin Cancer Res. 2024. PMID: 38980931
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Bruno T, De Nicola F, Iezzi S, Lecis D, D'Angelo C, Di Padova M, Corbi N, Dimiziani L, Zannini L, Jekimovs C, Scarsella M, Porrello A, Chersi A, Crescenzi M, Leonetti C, Khanna KK, Soddu S, Floridi A, Passananti C, Delia D, Fanciulli M. Bruno T, et al. Among authors: fanciulli m. Cancer Cell. 2006 Dec;10(6):473-86. doi: 10.1016/j.ccr.2006.10.012. Cancer Cell. 2006. PMID: 17157788 Free article.
Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.
Bruno T, Desantis A, Bossi G, Di Agostino S, Sorino C, De Nicola F, Iezzi S, Franchitto A, Benassi B, Galanti S, La Rosa F, Floridi A, Bellacosa A, Passananti C, Blandino G, Fanciulli M. Bruno T, et al. Among authors: fanciulli m. Cancer Cell. 2010 Aug 9;18(2):122-34. doi: 10.1016/j.ccr.2010.05.027. Cancer Cell. 2010. PMID: 20708154 Free article.
VDR primary targets by genome-wide transcriptional profiling.
Goeman F, De Nicola F, D'Onorio De Meo P, Pallocca M, Elmi B, Castrignanò T, Pesole G, Strano S, Blandino G, Fanciulli M, Muti P. Goeman F, et al. Among authors: fanciulli m. J Steroid Biochem Mol Biol. 2014 Sep;143:348-56. doi: 10.1016/j.jsbmb.2014.03.007. Epub 2014 Apr 13. J Steroid Biochem Mol Biol. 2014. PMID: 24726990 Free article.
Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Ponzoni M, Bossi G, Federico V, La Rosa F, Ricciardi MR, Lesma E, De Meo PD, Castrignanò T, Petrucci MT, Pisani F, Chesi M, Bergsagel PL, Floridi A, Tonon G, Passananti C, Blandino G, Fanciulli M. Desantis A, et al. Among authors: fanciulli m. EMBO J. 2015 May 5;34(9):1214-30. doi: 10.15252/embj.201489920. Epub 2015 Mar 14. EMBO J. 2015. PMID: 25770584 Free PMC article.
217 results