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FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs.
Wasserman JS, Faezov B, Patel KR, Kurimchak AM, Palacio SM, Glass DJ, Fowle H, McEwan BC, Xu Q, Zhao Z, Cressey L, Johnson N, Duncan JS, Kettenbach AN, Dunbrack RL Jr, Graña X. Wasserman JS, et al. Among authors: palacio sm. Nat Commun. 2024 Jul 10;15(1):5776. doi: 10.1038/s41467-024-50015-7. Nat Commun. 2024. PMID: 38982062 Free PMC article.
FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55⍺/PP2A phosphatase.
Wasserman JS, Faezov B, Patel KR, Kurimchak AN, Palacio SM, Fowle H, McEwan BC, Xu Q, Zhao Z, Cressey L, Johnson N, Duncan JS, Kettenbach AN, Dunbrack RL, Graña X. Wasserman JS, et al. Among authors: palacio sm. bioRxiv [Preprint]. 2023 Mar 17:2023.03.06.531310. doi: 10.1101/2023.03.06.531310. bioRxiv. 2023. PMID: 36945596 Free PMC article. Preprint.
19 results