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964 results

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E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy.
Ali I, Silva J, Casillas-Espinosa PM, Braine E, Yamakawa GR, Hudson MR, Brady RD, Major B, Thergarajan P, Haskali MB, Wright DK, Jupp B, Vivash L, Shultz SR, Mychasiuk R, Kwan P, Jones NC, Fukushima K, Sachdev P, Cheng JY, O'Brien TJ. Ali I, et al. Epilepsia. 2023 Oct;64(10):2806-2817. doi: 10.1111/epi.17735. Epub 2023 Aug 11. Epilepsia. 2023. PMID: 37539645
Image data harmonization tools for the analysis of post-traumatic epilepsy development in preclinical multisite MRI studies.
Bhagavatula S, Cabeen R, Harris NG, Gröhn O, Wright DK, Garner R, Bennett A, Alba C, Martinez A, Ndode-Ekane XE, Andrade P, Paananen T, Ciszek R, Immonen R, Manninen E, Puhakka N, Tohka J, Heiskanen M, Ali I, Shultz SR, Casillas-Espinosa PM, Yamakawa GR, Jones NC, Hudson MR, Silva JC, Braine EL, Brady RD, Santana-Gomez CE, Smith GD, Staba R, O'Brien TJ, Pitkänen A, Duncan D; EpiBioS4Rx investigators. Bhagavatula S, et al. Epilepsy Res. 2023 Sep;195:107201. doi: 10.1016/j.eplepsyres.2023.107201. Epub 2023 Aug 2. Epilepsy Res. 2023. PMID: 37562146 Free PMC article.
Phase II randomised placebo-controlled trial of sodium selenate as a disease-modifying treatment in chronic drug-resistant temporal lobe epilepsy: the SeLECT study protocol.
Vivash L, Johns H, Churilov L, MacPhail S, Casillas-Espinosa P, Malpas C, Shultz SR, Tailby C, Wijayath M, Reutens D, Gillinder L, Perucca P, Carney P, Nicolo JP, Lawn N, Kwan P, Velakoulis D, Hovens CM, O'Brien TJ. Vivash L, et al. BMJ Open. 2023 Oct 27;13(10):e075888. doi: 10.1136/bmjopen-2023-075888. BMJ Open. 2023. PMID: 37890967 Free PMC article.
Epilepsy phenotype and its reproducibility after lateral fluid percussion-induced traumatic brain injury in rats: Multicenter EpiBioS4Rx study project 1.
Ndode-Ekane XE, Ali I, Santana-Gomez C, Andrade P, Immonen R, Casillas-Espinosa P, Paananen T, Manninen E, Puhakka N, Smith G, Brady RD, Silva J, Braine E, Hudson M, Yamakawa GR, Jones NC, Shultz SR, Harris N, Wright DK, Gröhn O, Staba R, O'Brien TJ, Pitkänen A. Ndode-Ekane XE, et al. Epilepsia. 2024 Feb;65(2):511-526. doi: 10.1111/epi.17838. Epub 2023 Dec 12. Epilepsia. 2024. PMID: 38052475 Free article.
Biomarkers of Neurobiologic Recovery in Adults With Sport-Related Concussion.
O'Brien WT, Spitz G, Xie B, Major BP, Mutimer S, Giesler LP, Bain J, Evans LJ, Duarte Martins B, Piantella S, Alhassan A, Brady S, Cappellari D, Somma V, McColl T, Symons GF, Gore T, Sun M, Kuek T, Horan S, Bei M, Ponsford JL, Willmott C, Reyes J, Ashton NJ, Zetterberg H, Mitra B, O'Brien TJ, Shultz SR, McDonald SJ. O'Brien WT, et al. JAMA Netw Open. 2024 Jun 3;7(6):e2415983. doi: 10.1001/jamanetworkopen.2024.15983. JAMA Netw Open. 2024. PMID: 38848061 Free PMC article.
The Australian Traumatic Brain Injury Initiative: Systematic Review of Clinical Factors Associated with Outcomes in People with Moderate-Severe Traumatic Brain Injury.
McKimmie A, Keeves J, Gadowski A, Bagg MK, Antonic-Baker A, Hicks AJ, Hill R, Clarke N, Holland A, Veitch B, Fatovich D, Reeder S, Romero L, Ponsford JL, Lannin NA, O'Brien TJ, Cooper DJ, Rushworth N, Fitzgerald M, Gabbe BJ, Cameron PA; Australian Traumatic Brain Injury Initiative Investigators**; Australian Traumatic Brain Injury Initiative Investigators. McKimmie A, et al. Neurotrauma Rep. 2024 Jul 4;5(1):0. doi: 10.1089/neur.2023.0111. eCollection 2024. Neurotrauma Rep. 2024. PMID: 39081663 Review.
In vivo biomarkers of GABAergic function in epileptic rats treated with the GAT-1 inhibitor E2730.
Ali I, Jupp B, Hudson MR, Major B, Silva J, Yamakawa GR, Casillas-Espinosa PM, Braine E, Thergarajan P, Haskali MB, Vivash L, Brkljaca R, Shultz SR, Kwan P, Fukushima K, Sachdev P, Cheng JY, Mychasiuk R, Jones NC, Wright DK, OBrien TJ. Ali I, et al. Epilepsia. 2024 Nov;65(11):3376-3390. doi: 10.1111/epi.18119. Epub 2024 Sep 20. Epilepsia. 2024. PMID: 39302665
964 results