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PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity.
Tang S, Kim SW, Olsen-Dufour A, Pearson T, Freaney M, Singley E, Jenkins M, Burkard NJ, Wozniak A, Parcon P, Wu S, Morse CL, Jana S, Liow JS, Zoghbi SS, Vendruscolo JCM, Vendruscolo LF, Pike VW, Koob GF, Volkow ND, Innis RB. Tang S, et al. Among authors: jana s. Neuropsychopharmacology. 2024 Dec;50(2):444-451. doi: 10.1038/s41386-024-01988-y. Epub 2024 Sep 16. Neuropsychopharmacology. 2024. PMID: 39285225 Free PMC article.
[18F]SF51, a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans.
Yan X, Siméon FG, Liow JS, Morse CL, Jana S, Montero Santamaria JA, Jenkins M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: jana s. J Cereb Blood Flow Metab. 2024 Dec 9:271678X241304924. doi: 10.1177/0271678X241304924. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39654356 Free PMC article.
Development and Evaluation in Rat and Monkey of a Candidate Homochiral Radioligand for PET Studies of Brain Receptor Interacting Protein Kinase 1: [18F](S)-1-(5-(3-Fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)-2,2-dimethylpropan-1-one.
Jana S, Maqbool M, Yan X, Jakobsson JE, Lee AC, Liow JS, Zoghbi SS, Wu S, Long P, Innis RB, Telu S, Pike VW. Jana S, et al. ACS Chem Neurosci. 2025 Jan 2. doi: 10.1021/acschemneuro.4c00715. Online ahead of print. ACS Chem Neurosci. 2025. PMID: 39745023
1,099 results