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Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease.
Lee SHT, Garske KM, Arasu UT, Kar A, Miao Z, Alvarez M, Koka A, Darci-Maher N, Benhammou JN, Pan DZ, Örd T, Kaminska D, Männistö V, Heinonen S, Wabitsch M, Laakso M, Agopian VG, Pisegna JR, Pietiläinen KH, Pihlajamäki J, Kaikkonen MU, Pajukanta P. Lee SHT, et al. Among authors: kaikkonen mu. EBioMedicine. 2024 Aug;106:105232. doi: 10.1016/j.ebiom.2024.105232. Epub 2024 Jul 10. EBioMedicine. 2024. PMID: 38991381 Free PMC article.
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M. Cuartero S, et al. Among authors: kaikkonen mu. Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20. Nat Immunol. 2018. PMID: 30127433 Free PMC article.
Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia.
Laitinen P, Väänänen MA, Kolari IL, Mäkinen PI, Kaikkonen MU, Weinberg MS, Morris KV, Korhonen P, Malm T, Ylä-Herttuala S, Roberts TC, Turunen MP, Turunen TA. Laitinen P, et al. Among authors: kaikkonen mu. PLoS One. 2022 Mar 31;17(3):e0265948. doi: 10.1371/journal.pone.0265948. eCollection 2022. PLoS One. 2022. PMID: 35358280 Free PMC article.
Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
Leclerc S, Gupta A, Ruokolainen V, Chen JH, Kunnas K, Ekman AA, Niskanen H, Belevich I, Vihinen H, Turkki P, Perez-Berna AJ, Kapishnikov S, Mäntylä E, Harkiolaki M, Dufour E, Hytönen V, Pereiro E, McEnroe T, Fahy K, Kaikkonen MU, Jokitalo E, Larabell CA, Weinhardt V, Mattola S, Aho V, Vihinen-Ranta M. Leclerc S, et al. Among authors: kaikkonen mu. PLoS Pathog. 2024 Apr 15;20(4):e1011829. doi: 10.1371/journal.ppat.1011829. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38620036 Free PMC article.
Targeting IL-1 controls refractory pityriasis rubra pilaris.
Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, Kahlenberg JM, Mellett M, Navarini A, Nobbe S, Sarkar MK, Satyam A, Tsoi LC, French LE, Nilsson J, Linna-Kuosmanen S, Kaikkonen MU, Snijder B, Kellis M, Gudjonsson JE, Tsokos GC, Contassot E, Kolios AGA. Schmauch E, et al. Among authors: kaikkonen mu. Sci Adv. 2024 Jul 5;10(27):eado2365. doi: 10.1126/sciadv.ado2365. Epub 2024 Jul 3. Sci Adv. 2024. PMID: 38959302 Free PMC article.
123 results