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R1205H (Vicenza) causes conformational changes in the von Willebrand factor D'D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI.
Atiq F, Rawley O, O'Sullivan JM, Özbil M, Doherty D, Cooke N, Terraube V, Chion A, Amin A, Hulshof AM, Baci B, Byrne C, Aburawi HE, Lillicrap D, O'Donnell JS. Atiq F, et al. J Thromb Haemost. 2024 Oct;22(10):2752-2760. doi: 10.1016/j.jtha.2024.06.023. Epub 2024 Jul 10. J Thromb Haemost. 2024. PMID: 38996914 Free article.
VWF-ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion.
Fogarty H, Ahmad A, Atiq F, Doherty D, Ward S, Karampini E, Rehill A, Leon G, Byrne C, Geoghegan R, Conroy H, Byrne M, Budde U, Schneppenheim S, Sheehan C, Ngwenya N, Baker RI, Preston RJS, Tuohy E, McMahon C, O'Donnell JS. Fogarty H, et al. Among authors: atiq f. Blood Adv. 2023 Nov 28;7(22):6974-6989. doi: 10.1182/bloodadvances.2023010824. Blood Adv. 2023. PMID: 37773926 Free PMC article.
Novel functions for von Willebrand factor.
Atiq F, O'Donnell JS. Atiq F, et al. Blood. 2024 Sep 19;144(12):1247-1256. doi: 10.1182/blood.2023021915. Blood. 2024. PMID: 38728426 Review.
Patient-reported data on the severity of Von Willebrand disease.
van Kwawegen CB, Fijnvandraat K, Kruip MJHA, de Meris J, Schols SEM, Meijer K, van der Bom JG, Cnossen MH, van Galen KPM, Atiq F, Eikenboom J, Leebeek FWG; WiN study group. van Kwawegen CB, et al. Among authors: atiq f. Haemophilia. 2024 Nov;30(6):1348-1356. doi: 10.1111/hae.15103. Epub 2024 Oct 15. Haemophilia. 2024. PMID: 39403864 Free PMC article.
Genetic variants, thrombocytopenia, and clinical phenotype of type 2B von Willebrand disease: a median 16-year follow-up study.
van Kwawegen CB, Atiq F, Endenburg D, Fijnvandraat K, van Galen KPM, Cnossen MH, Schols SEM, Kruip MJHA, van Heerde WL, de Meris J, van der Bom JG, Eikenboom J, Meijer K, Leebeek FWG; WiN study group. van Kwawegen CB, et al. Among authors: atiq f. J Thromb Haemost. 2024 Dec;22(12):3460-3472. doi: 10.1016/j.jtha.2024.08.028. Epub 2024 Sep 28. J Thromb Haemost. 2024. PMID: 39343102 Free article.
Variant mapping using mass spectrometry-based proteotyping as a diagnostic tool in von Willebrand disease.
Kreft IC, van Duijl TT, van Kwawegen C, Atiq F, Phan W, Schuller MBP, Boon-Spijker M, van der Zwaan C, Meijer AB, Hoogendijk AJ, Bierings R, Eikenboom JCJ, Leebeek FWG, van den Biggelaar M; Willebrand in the Netherlands (WiN) study group. Kreft IC, et al. Among authors: atiq f. J Thromb Haemost. 2024 Jul;22(7):1894-1908. doi: 10.1016/j.jtha.2024.04.011. Epub 2024 Apr 27. J Thromb Haemost. 2024. PMID: 38679335 Free article.
Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies.
Atiq F, Blok R, van Kwawegen CB, Doherty D, Lavin M, van der Bom JG, O'Connell NM, de Meris J, Ryan K, Schols SEM, Byrne M, Heubel-Moenen FCJI, van Galen KPM, Preston RJS, Cnossen MH, Fijnvandraat K, Baker RI, Meijer K, James P, Di Paola J, Eikenboom J, Leebeek FWG, O'Donnell JS. Atiq F, et al. Blood. 2024 Apr 4;143(14):1414-1424. doi: 10.1182/blood.2023022457. Blood. 2024. PMID: 38142407 Free PMC article.
45 results