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R1205H (Vicenza) causes conformational changes in the von Willebrand factor D'D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI.
Atiq F, Rawley O, O'Sullivan JM, Özbil M, Doherty D, Cooke N, Terraube V, Chion A, Amin A, Hulshof AM, Baci B, Byrne C, Aburawi HE, Lillicrap D, O'Donnell JS. Atiq F, et al. Among authors: terraube v. J Thromb Haemost. 2024 Oct;22(10):2752-2760. doi: 10.1016/j.jtha.2024.06.023. Epub 2024 Jul 10. J Thromb Haemost. 2024. PMID: 38996914 Free article.
Cysteine-mutations in von Willebrand factor associated with increased clearance.
Schooten CJ, Tjernberg P, Westein E, Terraube V, Castaman G, Mourik JA, Hollestelle MJ, Vos HL, Bertina RM, Berg HM, Eikenboom JC, Lenting PJ, Denis CV. Schooten CJ, et al. Among authors: terraube v. J Thromb Haemost. 2005 Oct;3(10):2228-37. doi: 10.1111/j.1538-7836.2005.01571.x. J Thromb Haemost. 2005. PMID: 16194200 Free article.
A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
Tu C, Terraube V, Tam AS, Stochaj W, Fennell BJ, Lin L, Stahl M, LaVallie ER, Somers W, Finlay WJ, Mosyak L, Bard J, Cunningham O. Tu C, et al. Among authors: terraube v. J Biol Chem. 2016 Jan 15;291(3):1267-76. doi: 10.1074/jbc.M115.688010. Epub 2015 Oct 29. J Biol Chem. 2016. PMID: 26515064 Free PMC article.
Erythroferrone inhibits the induction of hepcidin by BMP6.
Arezes J, Foy N, McHugh K, Sawant A, Quinkert D, Terraube V, Brinth A, Tam M, LaVallie ER, Taylor S, Armitage AE, Pasricha SR, Cunningham O, Lambert M, Draper SJ, Jasuja R, Drakesmith H. Arezes J, et al. Among authors: terraube v. Blood. 2018 Oct 4;132(14):1473-1477. doi: 10.1182/blood-2018-06-857995. Epub 2018 Aug 10. Blood. 2018. PMID: 30097509 Free PMC article.
14 results