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Synergistic effect of concurrent high molecular risk mutations and lower JAK2 mutant variant allele frequencies on prognosis in patients with myelofibrosis-insights from a multicenter study.
Wang YH, Wei CH, Lin CC, Gurnari C, Awada H, Benajiba L, Daltro de Oliveira R, Soret-Dulphy J, Cassinat B, Zucenka A, Mosquera Orgueira A, Yuan CT, Lee SH, Yao CY, Gurashi K, Hou HA, Batta K, Pérez Encinas MM, Chou WC, Maciejewski JP, Wiseman DH, Kiladjian JJ, Tien HF. Wang YH, et al. Among authors: gurashi k. Leukemia. 2024 Oct 4. doi: 10.1038/s41375-024-02422-4. Online ahead of print. Leukemia. 2024. PMID: 39367172
Higher MDMX expression was associated with hypomethylating agent resistance and inferior survival in MDS patients, inferring it a potential therapeutic target.
Wang YH, Lin CC, Gurashi K, Wingelhofer B, Amaral FMR, Yao CY, Hsieh HT, Liu MC, Hou HA, Chou WC, Batta K, Wiseman DH, Tien HF. Wang YH, et al. Among authors: gurashi k. Leukemia. 2023 Dec;37(12):2507-2511. doi: 10.1038/s41375-023-02044-2. Epub 2023 Nov 2. Leukemia. 2023. PMID: 37919605 No abstract available.
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils.
Huerga Encabo H, Aramburu IV, Garcia-Albornoz M, Piganeau M, Wood H, Song A, Ferrelli A, Sharma A, Minutti CM, Domart MC, Papazoglou D, Gurashi K, Llorian Sopena M, Goldstone R, Fallesen T, Wang Q, Ariza-McNaughton L, Wiseman DH, Batta K, Gupta R, Papayannopoulos V, Bonnet D. Huerga Encabo H, et al. Among authors: gurashi k. Cell Stem Cell. 2023 Jun 1;30(6):781-799.e9. doi: 10.1016/j.stem.2023.05.004. Cell Stem Cell. 2023. PMID: 37267914 Free article.