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Discovery of novel 6-(piperidin-1-ylsulfonyl)-2H-chromenes targeting α-glucosidase, α-amylase, and PPAR-γ: Design, synthesis, virtual screening, and anti-diabetic activity for type 2 diabetes mellitus.
Thabet HK, Abusaif MS, Imran M, Helal MH, Alaqel SI, Alshehri A, Mohd AA, Ammar YA, Ragab A. Thabet HK, et al. Among authors: helal mh. Comput Biol Chem. 2024 Aug;111:108097. doi: 10.1016/j.compbiolchem.2024.108097. Epub 2024 May 17. Comput Biol Chem. 2024. PMID: 38772048
Discovery of new anti-diabetic potential agents based on paracetamol incorporating sulfa-drugs: Design, synthesis, α-amylase, and α-glucosidase inhibitors with molecular docking simulation.
Khamees Thabet H, Ragab A, Imran M, Helal MH, Ibrahim Alaqel S, Alshehri A, Ash Mohd A, Rakan Alshammari M, S Abusaif M, A Ammar Y. Khamees Thabet H, et al. Among authors: helal mh. Eur J Med Chem. 2024 Sep 5;275:116589. doi: 10.1016/j.ejmech.2024.116589. Epub 2024 Jun 8. Eur J Med Chem. 2024. PMID: 38878516
44 results