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Page 1
Delayed treatment of cynomolgus macaques with a FVM04/CA45 monoclonal antibody cocktail provides complete protection against lethal Sudan virus infection.
Chan M, Warner BM, Audet J, Barker D, Tailor N, Vendramelli R, Truong T, Tierney K, Boese AS, Qiu H, Holtsberg FW, Aman J, Kodihalli S, Kobasa D. Chan M, et al. Among authors: holtsberg fw. J Virol. 2024 Aug 20;98(8):e0124223. doi: 10.1128/jvi.01242-23. Epub 2024 Jul 16. J Virol. 2024. PMID: 39012096 Free PMC article.
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
Wirchnianski AS, Nyakatura EK, Herbert AS, Kuehne AI, Abbasi SA, Florez C, Storm N, McKay LGA, Dailey L, Kuang E, Abelson DM, Wec AZ, Chakraborti S, Holtsberg FW, Shulenin S, Bornholdt ZA, Aman MJ, Honko AN, Griffiths A, Dye JM, Chandran K, Lai JR. Wirchnianski AS, et al. Among authors: holtsberg fw. PLoS Pathog. 2024 Apr 11;20(4):e1012134. doi: 10.1371/journal.ppat.1012134. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38603762 Free PMC article.
Alkynyl nicotinamides show antileukemic activity in drug-resistant acute myeloid leukemia.
Ramdas B, Dayal N, Pandey R, Larocque E, Kanumuri R, Pasupuleti SK, Liu S, Kanellopoulou C, Chu EFY, Mohallem R, Virani S, Chopra G, Aryal UK, Lapidus R, Wan J, Emadi A, Haneline LS, Holtsberg FW, Aman MJ, Sintim HO, Kapur R. Ramdas B, et al. Among authors: holtsberg fw. J Clin Invest. 2024 Jun 17;134(12):e169245. doi: 10.1172/JCI169245. J Clin Invest. 2024. PMID: 38950330 Free PMC article.
Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections.
Adhikari RP, Alem F, Kemboi D, Kanipakala T, Sherchand SP, Kailasan S, Purcell BK, Heine HS, Russell-Lodrigue K, Etobayeva I, Howell KA, Vu H, Shulenin S, Holtsberg FW, Roy CJ, Hakami RM, Nelson DC, Aman MJ. Adhikari RP, et al. Among authors: holtsberg fw. medRxiv [Preprint]. 2024 Sep 25:2024.09.23.24313920. doi: 10.1101/2024.09.23.24313920. medRxiv. 2024. PMID: 39398995 Free PMC article. Preprint.
Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors.
Khatri U, Dayal N, Hu X, Larocque E, Naganna N, Shen T, Liu X, Holtsberg FW, Aman MJ, Sintim HO, Wu J. Khatri U, et al. Among authors: holtsberg fw. Mol Cancer Ther. 2023 Jun 1;22(6):717-725. doi: 10.1158/1535-7163.MCT-22-0629. Mol Cancer Ther. 2023. PMID: 37070927 Free PMC article.
Rapid detection of an Ebola biomarker with optical microring resonators.
Qavi AJ, Meserve K, Aman MJ, Vu H, Zeitlin L, Dye JM, Froude JW, Leung DW, Yang L, Holtsberg FW, Bailey RC, Amarasinghe GK. Qavi AJ, et al. Among authors: holtsberg fw. Cell Rep Methods. 2022 Jun 8;2(6):100234. doi: 10.1016/j.crmeth.2022.100234. eCollection 2022 Jun 20. Cell Rep Methods. 2022. PMID: 35784644 Free PMC article.
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