Koutmos M - Search Results

1

A Noble Metal Substitution Leads to B₁₂ Cofactor Mimicry by a Rhodibalamin.

Ruetz M, Mascarenhas R, Widner F, Kieninger C, Koutmos M, Kräutler B, Banerjee R. Ruetz M, et al. Among authors: koutmos m. Biochemistry. 2024 Aug 6;63(15):1955-1962. doi: 10.1021/acs.biochem.4c00216. Epub 2024 Jul 16. Biochemistry. 2024. PMID: 39012171

2

Adenosine modifications impede SARS-CoV-2 RNA-dependent RNA transcription.

Snyder LR, Kilde I, Nemudryi A, Wiedenheft B, Koutmos M, Koutmou KS. Snyder LR, et al. Among authors: koutmos m. RNA. 2024 Aug 16;30(9):1141-1150. doi: 10.1261/rna.079991.124. RNA. 2024. PMID: 38942480 Free PMC article.

3

Structural basis of S-adenosylmethionine-dependent allosteric transition from active to inactive states in methylenetetrahydrofolate reductase.

Yamada K, Mendoza J, Koutmos M. Yamada K, et al. Among authors: koutmos m. Nat Commun. 2024 Jun 17;15(1):5167. doi: 10.1038/s41467-024-49327-5. Nat Commun. 2024. PMID: 38886362 Free PMC article.

4

Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.

DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM. DeAngelo SL, et al. Among authors: koutmos m. bioRxiv [Preprint]. 2024 Aug 27:2024.03.29.587381. doi: 10.1101/2024.03.29.587381. bioRxiv. 2024. PMID: 38617233 Free PMC article. Preprint.

5

The protein-only RNase Ps, endonucleases that cleave pre-tRNA: Biological relevance, molecular architectures, substrate recognition and specificity, and protein interactomes.

Wilhelm CA, Kaitany K, Kelly A, Yacoub M, Koutmos M. Wilhelm CA, et al. Among authors: koutmos m. Wiley Interdiscip Rev RNA. 2024 Mar-Apr;15(2):e1836. doi: 10.1002/wrna.1836. Wiley Interdiscip Rev RNA. 2024. PMID: 38453211

6

Collision-Induced Unfolding Reveals Disease-Associated Stability Shifts in Mitochondrial Transfer Ribonucleic Acids.

Anders AG, Tidwell ED, Gadkari VV, Koutmos M, Ruotolo BT. Anders AG, et al. Among authors: koutmos m. J Am Chem Soc. 2024 Feb 21;146(7):4412-4420. doi: 10.1021/jacs.3c09230. Epub 2024 Feb 8. J Am Chem Soc. 2024. PMID: 38329282

7

Fluorescent Ligand Equilibrium Displacement: A High-Throughput Method for Identification of FMN Riboswitch-Binding Small Molecules.

Tidwell ED, Kilde IR, Leskaj S, Koutmos M. Tidwell ED, et al. Among authors: koutmos m. Int J Mol Sci. 2024 Jan 6;25(2):0. doi: 10.3390/ijms25020735. Int J Mol Sci. 2024. PMID: 38255809 Free PMC article.

8

Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.

Mendoza J, Purchal M, Yamada K, Koutmos M. Mendoza J, et al. Among authors: koutmos m. Nat Commun. 2023 Oct 11;14(1):6365. doi: 10.1038/s41467-023-42037-4. Nat Commun. 2023. PMID: 37821448 Free PMC article.

9

Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P.

Wilhelm CA, Mallik L, Kelly AL, Brotzman S, Mendoza J, Anders AG, Leskaj S, Castillo C, Ruotolo BT, Cianfrocco MA, Koutmos M. Wilhelm CA, et al. Among authors: koutmos m. J Biol Chem. 2023 Nov;299(11):105327. doi: 10.1016/j.jbc.2023.105327. Epub 2023 Oct 6. J Biol Chem. 2023. PMID: 37806495 Free PMC article.

10

Selenoproteins and tRNA-Sec: regulators of cancer redox homeostasis.

DeAngelo SL, Győrffy B, Koutmos M, Shah YM. DeAngelo SL, et al. Among authors: koutmos m. Trends Cancer. 2023 Dec;9(12):1006-1018. doi: 10.1016/j.trecan.2023.08.003. Epub 2023 Sep 15. Trends Cancer. 2023. PMID: 37716885 Free PMC article. Review.

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