Halbert CL - Search Results

1

Split intein-mediated protein trans-splicing to express large dystrophins.

Tasfaout H, Halbert CL, McMillen TS, Allen JM, Reyes TR, Flint GV, Grimm D, Hauschka SD, Regnier M, Chamberlain JS. Tasfaout H, et al. Among authors: halbert cl. Nature. 2024 Aug;632(8023):192-200. doi: 10.1038/s41586-024-07710-8. Epub 2024 Jul 17. Nature. 2024. PMID: 39020181 Free PMC article.

2

Comparison of dystrophin expression following gene editing and gene replacement in an aged preclinical DMD animal model.

Bengtsson NE, Crudele JM, Klaiman JM, Halbert CL, Hauschka SD, Chamberlain JS. Bengtsson NE, et al. Among authors: halbert cl. Mol Ther. 2022 Jun 1;30(6):2176-2185. doi: 10.1016/j.ymthe.2022.02.003. Epub 2022 Feb 8. Mol Ther. 2022. PMID: 35143959 Free PMC article.

3

AAV6 Vector Production and Purification for Muscle Gene Therapy.

Halbert CL, Allen JM, Chamberlain JS. Halbert CL, et al. Methods Mol Biol. 2018;1687:257-266. doi: 10.1007/978-1-4939-7374-3_18. Methods Mol Biol. 2018. PMID: 29067669

4

Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model.

Wang Z, Halbert CL, Lee D, Butts T, Tapscott SJ, Storb R, Miller AD. Wang Z, et al. Among authors: halbert cl. Gene Ther. 2014 Apr;21(4):363-70. doi: 10.1038/gt.2014.4. Epub 2014 Feb 6. Gene Ther. 2014. PMID: 24500525 Free PMC article.

5

Successful regional delivery and long-term expression of a dystrophin gene in canine muscular dystrophy: a preclinical model for human therapies.

Wang Z, Storb R, Halbert CL, Banks GB, Butts TM, Finn EE, Allen JM, Miller AD, Chamberlain JS, Tapscott SJ. Wang Z, et al. Among authors: halbert cl. Mol Ther. 2012 Aug;20(8):1501-7. doi: 10.1038/mt.2012.111. Epub 2012 Jun 12. Mol Ther. 2012. PMID: 22692496 Free PMC article.

6

Lung cancer in mice induced by the jaagsiekte sheep retrovirus envelope protein is not maintained by rare cancer stem cells, but tumorigenicity does correlate with Wnt pathway activation.

Vaughan AE, Halbert CL, Wootton SK, Miller AD. Vaughan AE, et al. Among authors: halbert cl. Mol Cancer Res. 2012 Jan;10(1):86-95. doi: 10.1158/1541-7786.MCR-11-0285. Epub 2011 Nov 7. Mol Cancer Res. 2012. PMID: 22064658 Free article.

7

Jaagsiekte sheep retrovirus and enzootic nasal tumor virus promoters drive gene expression in all airway epithelial cells of mice but only induce tumors in the alveolar region of the lungs.

Yu DL, Linnerth-Petrik NM, Halbert CL, Walsh SR, Miller AD, Wootton SK. Yu DL, et al. Among authors: halbert cl. J Virol. 2011 Aug;85(15):7535-45. doi: 10.1128/JVI.00400-11. Epub 2011 May 18. J Virol. 2011. PMID: 21593165 Free PMC article.

8

Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production.

Halbert CL, Metzger MJ, Lam SL, Miller AD. Halbert CL, et al. Gene Ther. 2011 Apr;18(4):411-7. doi: 10.1038/gt.2010.167. Epub 2010 Dec 16. Gene Ther. 2011. PMID: 21160534 Free PMC article.

9

Expression of human alpha1-antitrypsin in mice and dogs following AAV6 vector-mediated gene transfer to the lungs.

Halbert CL, Madtes DK, Vaughan AE, Wang Z, Storb R, Tapscott SJ, Miller AD. Halbert CL, et al. Mol Ther. 2010 Jun;18(6):1165-72. doi: 10.1038/mt.2010.51. Epub 2010 Apr 6. Mol Ther. 2010. PMID: 20372105 Free PMC article.

10

High-efficiency promoter-dependent transduction by adeno-associated virus type 6 vectors in mouse lung.

Halbert CL, Lam SL, Miller AD. Halbert CL, et al. Hum Gene Ther. 2007 Apr;18(4):344-54. doi: 10.1089/hum.2006.182. Hum Gene Ther. 2007. PMID: 17430088 Free PMC article.

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