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Small-Molecule Disruptors of the Interaction between Calcium- and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents.
Golla K, Yasgar A, Manjuprasanna VN, Naik MU, Baljinnyam B, Zakharov AV, Jain S, Rai G, Jadhav A, Simeonov A, Naik UP. Golla K, et al. Among authors: rai g. ACS Pharmacol Transl Sci. 2024 May 29;7(7):1971-1982. doi: 10.1021/acsptsci.4c00026. eCollection 2024 Jul 12. ACS Pharmacol Transl Sci. 2024. PMID: 39022362
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
Rai G, Sayed AA, Lea WA, Luecke HF, Chakrapani H, Prast-Nielsen S, Jadhav A, Leister W, Shen M, Inglese J, Austin CP, Keefer L, Arnér ES, Simeonov A, Maloney DJ, Williams DL, Thomas CJ. Rai G, et al. J Med Chem. 2009 Oct 22;52(20):6474-83. doi: 10.1021/jm901021k. J Med Chem. 2009. PMID: 19761212 Free PMC article.
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB 2nd, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR. Kenyon V, et al. Among authors: rai g. J Med Chem. 2011 Aug 11;54(15):5485-97. doi: 10.1021/jm2005089. Epub 2011 Jul 8. J Med Chem. 2011. PMID: 21739938 Free PMC article.
520 results