Pannecouque C - Search Results

1

Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles.

Sun Y, Zhou Z, Shi Z, Zhao F, Xie M, Zhuo Z, De Clercq E, Pannecouque C, Kang D, Zhan P, Liu X. Sun Y, et al. Among authors: pannecouque c. Acta Pharm Sin B. 2024 Jul;14(7):3110-3124. doi: 10.1016/j.apsb.2024.03.021. Epub 2024 Mar 27. Acta Pharm Sin B. 2024. PMID: 39027243 Free PMC article.

2

New class of HIV integrase inhibitors that block viral replication in cell culture.

Pannecouque C, Pluymers W, Van Maele B, Tetz V, Cherepanov P, De Clercq E, Witvrouw M, Debyser Z. Pannecouque C, et al. Curr Biol. 2002 Jul 23;12(14):1169-77. doi: 10.1016/s0960-9822(02)00952-1. Curr Biol. 2002. PMID: 12176326 Free article.

3

Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives.

Pluymers W, Pais G, Van Maele B, Pannecouque C, Fikkert V, Burke TR Jr, De Clercq E, Witvrouw M, Neamati N, Debyser Z. Pluymers W, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2002 Oct;46(10):3292-7. doi: 10.1128/AAC.46.10.3292-3297.2002. Antimicrob Agents Chemother. 2002. PMID: 12234864 Free PMC article.

4

env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors.

Fikkert V, Cherepanov P, Van Laethem K, Hantson A, Van Remoortel B, Pannecouque C, De Clercq E, Debyser Z, Vandamme AM, Witvrouw M. Fikkert V, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2002 Dec;46(12):3954-62. doi: 10.1128/AAC.46.12.3954-3962.2002. Antimicrob Agents Chemother. 2002. PMID: 12435701 Free PMC article.

5

N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action.

Lagoja IM, Pannecouque C, Van Aerschot A, Witvrouw M, Debyser Z, Balzarini J, Herdewijn P, De Clercq E. Lagoja IM, et al. Among authors: pannecouque c. J Med Chem. 2003 Apr 10;46(8):1546-53. doi: 10.1021/jm0211117. J Med Chem. 2003. PMID: 12672256

6

Antiretroviral activity of semisynthetic derivatives of glycopeptide antibiotics.

Balzarini J, Pannecouque C, De Clercq E, Pavlov AY, Printsevskaya SS, Miroshnikova OV, Reznikova MI, Preobrazhenskaya MN. Balzarini J, et al. Among authors: pannecouque c. J Med Chem. 2003 Jun 19;46(13):2755-64. doi: 10.1021/jm0300882. J Med Chem. 2003. PMID: 12801238

7

Nonnucleoside HIV-1 reverse transcriptase inhibitors: Part I. Synthesis and structure-activity relationship of 1-alkoxymethyl-5-alkyl-6-naphthylmethyl uracils as HEPT analogues.

Meng G, Chen FE, De Clercq E, Balzarini J, Pannecouque C. Meng G, et al. Among authors: pannecouque c. Chem Pharm Bull (Tokyo). 2003 Jul;51(7):779-89. doi: 10.1248/cpb.51.779. Chem Pharm Bull (Tokyo). 2003. PMID: 12843582 Free article.

8

Inhibition of human immunodeficiency virus by a new class of pyridine oxide derivatives.

Stevens M, Pannecouque C, De Clercq E, Balzarini J. Stevens M, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2003 Sep;47(9):2951-7. doi: 10.1128/AAC.47.9.2951-2957.2003. Antimicrob Agents Chemother. 2003. PMID: 12937000 Free PMC article.

9

Novel human immunodeficiency virus (HIV) inhibitors that have a dual mode of anti-HIV action.

Stevens M, Pannecouque C, De Clercq E, Balzarini J. Stevens M, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2003 Oct;47(10):3109-16. doi: 10.1128/AAC.47.10.3109-3116.2003. Antimicrob Agents Chemother. 2003. PMID: 14506017 Free PMC article.

10

Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.

Fikkert V, Van Maele B, Vercammen J, Hantson A, Van Remoortel B, Michiels M, Gurnari C, Pannecouque C, De Maeyer M, Engelborghs Y, De Clercq E, Debyser Z, Witvrouw M. Fikkert V, et al. Among authors: pannecouque c. J Virol. 2003 Nov;77(21):11459-70. doi: 10.1128/jvi.77.21.11459-11470.2003. J Virol. 2003. PMID: 14557631 Free PMC article.

Grobler, A. Espeseth, L. Gabryelski, W. Schleif, C. Blau, and M. D. Miller, Science 287:646-650, 2000). We have now studied the development of antiviral resistance to L-708,906 by growing HIV-1 strains in the presence of increasing concentrations of the compound. ...Intere …

Grobler, A. Espeseth, L. Gabryelski, W. Schleif, C. Blau, and M. D. Miller, Science 287:646-650, 2000). We have now studied the devel …

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