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T/myeloid MPAL: origin and pathogenesis.
McCormack MP. McCormack MP. Blood. 2022 Jan 20;139(3):313-315. doi: 10.1182/blood.2021014129. Blood. 2022. PMID: 35050331 Free PMC article. No abstract available.
T-ALL can evolve to oncogene independence.
Abdulla H, Vo A, Shields BJ, Davies TJ, Jackson JT, Alserihi R, Viney EM, Wong T, Yan F, Wong NC, Demoen L, Curtis DJ, Alexander WS, Van Vlierberghe P, Dickins RA, McCormack MP. Abdulla H, et al. Among authors: mccormack mp. Leukemia. 2021 Aug;35(8):2205-2219. doi: 10.1038/s41375-021-01120-9. Epub 2021 Jan 22. Leukemia. 2021. PMID: 33483615
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
Amann-Zalcenstein D, Tian L, Schreuder J, Tomei S, Lin DS, Fairfax KA, Bolden JE, McKenzie MD, Jarratt A, Hilton A, Jackson JT, Di Rago L, McCormack MP, de Graaf CA, Stonehouse O, Taoudi S, Alexander WS, Nutt SL, Ritchie ME, Ng AP, Naik SH. Amann-Zalcenstein D, et al. Among authors: mccormack mp. Nat Immunol. 2020 Dec;21(12):1574-1584. doi: 10.1038/s41590-020-0799-x. Epub 2020 Oct 19. Nat Immunol. 2020. PMID: 33077975
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.
Carmichael CL, Wang J, Nguyen T, Kolawole O, Benyoucef A, De Mazière C, Milne AR, Samuel S, Gillinder K, Hediyeh-Zadeh S, Vo ANQ, Huang Y, Knezevic K, McInnes WRL, Shields BJ, Mitchell H, Ritchie ME, Lammens T, Lintermans B, Van Vlierberghe P, Wong NC, Haigh K, Thoms JAI, Toulmin E, Curtis DJ, Oxley EP, Dickins RA, Beck D, Perkins A, McCormack MP, Davis MJ, Berx G, Zuber J, Pimanda JE, Kile BT, Goossens S, Haigh JJ. Carmichael CL, et al. Among authors: mccormack mp. Blood. 2020 Aug 20;136(8):957-973. doi: 10.1182/blood.2019002548. Blood. 2020. PMID: 32369597 Free PMC article.
43 results