Leone TC - Search Results

1

SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice.

Berger JH, Matsuura TR, Bowman CE, Taing R, Patel J, Lai L, Leone TC, Reagan JD, Haldar SM, Arany Z, Kelly DP. Berger JH, et al. Among authors: leone tc. Circ Res. 2024 Aug 16;135(5):632-634. doi: 10.1161/CIRCRESAHA.124.324823. Epub 2024 Jul 23. Circ Res. 2024. PMID: 39041214 No abstract available.

2

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders.

Leone TC, Weinheimer CJ, Kelly DP. Leone TC, et al. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7473-8. doi: 10.1073/pnas.96.13.7473. Proc Natl Acad Sci U S A. 1999. PMID: 10377439 Free PMC article.

3

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth.

Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP. Barger PM, et al. Among authors: leone tc. J Clin Invest. 2000 Jun;105(12):1723-30. doi: 10.1172/JCI9056. J Clin Invest. 2000. PMID: 10862787 Free PMC article.

4

Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training.

Horowitz JF, Leone TC, Feng W, Kelly DP, Klein S. Horowitz JF, et al. Among authors: leone tc. Am J Physiol Endocrinol Metab. 2000 Aug;279(2):E348-55. doi: 10.1152/ajpendo.2000.279.2.E348. Am J Physiol Endocrinol Metab. 2000. PMID: 10913035 Free article. Clinical Trial.

5

Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle.

Schaeffer PJ, Wende AR, Magee CJ, Neilson JR, Leone TC, Chen F, Kelly DP. Schaeffer PJ, et al. Among authors: leone tc. J Biol Chem. 2004 Sep 17;279(38):39593-603. doi: 10.1074/jbc.M403649200. Epub 2004 Jul 19. J Biol Chem. 2004. PMID: 15262994 Free article.

6

Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization.

Luptak I, Balschi JA, Xing Y, Leone TC, Kelly DP, Tian R. Luptak I, et al. Among authors: leone tc. Circulation. 2005 Oct 11;112(15):2339-46. doi: 10.1161/CIRCULATIONAHA.105.534594. Epub 2005 Oct 3. Circulation. 2005. PMID: 16203912

7

Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.

Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP. Lai L, et al. Among authors: leone tc. Genes Dev. 2008 Jul 15;22(14):1948-61. doi: 10.1101/gad.1661708. Genes Dev. 2008. PMID: 18628400 Free PMC article.

8

Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.

Banke NH, Wende AR, Leone TC, O'Donnell JM, Abel ED, Kelly DP, Lewandowski ED. Banke NH, et al. Among authors: leone tc. Circ Res. 2010 Jul 23;107(2):233-41. doi: 10.1161/CIRCRESAHA.110.221713. Epub 2010 Jun 3. Circ Res. 2010. PMID: 20522803 Free PMC article.

9

Toll-like receptor-mediated inflammatory signaling reprograms cardiac energy metabolism by repressing peroxisome proliferator-activated receptor γ coactivator-1 signaling.

Schilling J, Lai L, Sambandam N, Dey CE, Leone TC, Kelly DP. Schilling J, et al. Among authors: leone tc. Circ Heart Fail. 2011 Jul;4(4):474-82. doi: 10.1161/CIRCHEARTFAILURE.110.959833. Epub 2011 May 10. Circ Heart Fail. 2011. PMID: 21558447 Free PMC article.

10

Transcriptional control of cardiac fuel metabolism and mitochondrial function.

Leone TC, Kelly DP. Leone TC, et al. Cold Spring Harb Symp Quant Biol. 2011;76:175-82. doi: 10.1101/sqb.2011.76.011965. Epub 2011 Nov 17. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22096028 Free PMC article. Review.

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