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Page 1
Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation.
Druso JE, MacPherson MB, Chia SB, Elko E, Aboushousha R, Seward DJ, Abdelhamid H, Erickson C, Corteselli E, Tarte M, Peng Z, Bernier D, Zito E, Shoulders MD, Thannickal VJ, Huang S, van der Vliet A, Anathy V, Janssen-Heininger YMW. Druso JE, et al. Among authors: aboushousha r. Am J Respir Cell Mol Biol. 2024 Nov;71(5):589-602. doi: 10.1165/rcmb.2023-0379OC. Am J Respir Cell Mol Biol. 2024. PMID: 39042020
The glutathione S-transferase Gstt1 drives survival and dissemination in metastases.
Ferrer CM, Cho HM, Boon R, Bernasocchi T, Wong LP, Cetinbas M, Haggerty ER, Mitsiades I, Wojtkiewicz GR, McLoughlin DE, Aboushousha R, Abdelhamid H, Kugel S, Rheinbay E, Sadreyev R, Juric D, Janssen-Heininger YMW, Mostoslavsky R. Ferrer CM, et al. Among authors: aboushousha r. Nat Cell Biol. 2024 Jun;26(6):975-990. doi: 10.1038/s41556-024-01426-7. Epub 2024 Jun 11. Nat Cell Biol. 2024. PMID: 38862786
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2.
van de Wetering C, Manuel AM, Sharafi M, Aboushousha R, Qian X, Erickson C, MacPherson M, Chan G, Adcock IM, ZounematKermani N, Schleich F, Louis R, Bohrnsen E, D'Alessandro A, Wouters EF, Reynaert NL, Li J, Wolf CR, Henderson CJ, Lundblad LKA, Poynter ME, Dixon AE, Irvin CG, van der Vliet A, van der Velden JL, Janssen-Heininger YM. van de Wetering C, et al. Among authors: aboushousha r. Redox Biol. 2021 Nov;47:102160. doi: 10.1016/j.redox.2021.102160. Epub 2021 Oct 3. Redox Biol. 2021. PMID: 34624602 Free PMC article.
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, Seward DJ, Janssen-Heininger YMW. Aboushousha R, et al. FASEB J. 2021 May;35(5):e21525. doi: 10.1096/fj.202002687RR. FASEB J. 2021. PMID: 33817836 Free PMC article.
Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.
Manuel AM, van de Wetering C, MacPherson M, Erickson C, Murray C, Aboushousha R, van der Velden J, Dixon AE, Poynter ME, Irvin CG, Taatjes DJ, van der Vliet A, Anathy V, Janssen-Heininger YMW. Manuel AM, et al. Among authors: aboushousha r. Am J Respir Cell Mol Biol. 2021 Jun;64(6):709-721. doi: 10.1165/rcmb.2020-0512OC. Am J Respir Cell Mol Biol. 2021. PMID: 33662229 Free PMC article.
Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling.
Chia SB, Nolin JD, Aboushousha R, Erikson C, Irvin CG, Poynter ME, van der Velden J, Taatjes DJ, van der Vliet A, Anathy V, Janssen-Heininger YMW. Chia SB, et al. Among authors: aboushousha r. Redox Biol. 2020 Oct;37:101720. doi: 10.1016/j.redox.2020.101720. Epub 2020 Sep 14. Redox Biol. 2020. PMID: 32971362 Free PMC article.
Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.
van de Wetering C, Aboushousha R, Manuel AM, Chia SB, Erickson C, MacPherson MB, van der Velden JL, Anathy V, Dixon AE, Irvin CG, Poynter ME, van der Vliet A, Wouters EFM, Reynaert NL, Janssen-Heininger YMW. van de Wetering C, et al. Among authors: aboushousha r. J Immunol. 2020 Feb 15;204(4):763-774. doi: 10.4049/jimmunol.1901086. Epub 2020 Jan 10. J Immunol. 2020. PMID: 31924651 Free PMC article.
Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.
Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger YMW. Chia SB, et al. Among authors: aboushousha r. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6. Am J Physiol Cell Physiol. 2020. PMID: 31693398 Free PMC article.
16 results