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Page 1
Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation.
Druso JE, MacPherson MB, Chia SB, Elko E, Aboushousha R, Seward DJ, Abdelhamid H, Erickson C, Corteselli E, Tarte M, Peng Z, Bernier D, Zito E, Shoulders MD, Thannickal VJ, Huang S, van der Vliet A, Anathy V, Janssen-Heininger YMW. Druso JE, et al. Among authors: chia sb. Am J Respir Cell Mol Biol. 2024 Nov;71(5):589-602. doi: 10.1165/rcmb.2023-0379OC. Am J Respir Cell Mol Biol. 2024. PMID: 39042020
Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.
Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, Lundblad LK, Ho YS, Anathy V, Irvin CG, Wouters EF, Reynaert NL, Dixon AE, van der Vliet A, Poynter ME, Janssen-Heininger YM. Hoffman SM, et al. Among authors: chia sb. Am J Respir Cell Mol Biol. 2016 Sep;55(3):377-86. doi: 10.1165/rcmb.2015-0401OC. Am J Respir Cell Mol Biol. 2016. PMID: 27035878 Free PMC article.
Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells.
Jones JT, Qian X, van der Velden JL, Chia SB, McMillan DH, Flemer S, Hoffman SM, Lahue KG, Schneider RW, Nolin JD, Anathy V, van der Vliet A, Townsend DM, Tew KD, Janssen-Heininger YM. Jones JT, et al. Among authors: chia sb. Redox Biol. 2016 Aug;8:375-82. doi: 10.1016/j.redox.2016.03.005. Epub 2016 Mar 26. Redox Biol. 2016. PMID: 27058114 Free PMC article.
Reducing protein oxidation reverses lung fibrosis.
Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW. Anathy V, et al. Among authors: chia sb. Nat Med. 2018 Aug;24(8):1128-1135. doi: 10.1038/s41591-018-0090-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988126 Free PMC article.
Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.
Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW. Elko EA, et al. Among authors: chia sb. Antioxid Redox Signal. 2019 Nov 10;31(14):1070-1091. doi: 10.1089/ars.2019.7752. Epub 2019 Apr 5. Antioxid Redox Signal. 2019. PMID: 30799628 Free PMC article. Review.
Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.
Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger YMW. Chia SB, et al. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6. Am J Physiol Cell Physiol. 2020. PMID: 31693398 Free PMC article.
Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling.
Chia SB, Nolin JD, Aboushousha R, Erikson C, Irvin CG, Poynter ME, van der Velden J, Taatjes DJ, van der Vliet A, Anathy V, Janssen-Heininger YMW. Chia SB, et al. Redox Biol. 2020 Oct;37:101720. doi: 10.1016/j.redox.2020.101720. Epub 2020 Sep 14. Redox Biol. 2020. PMID: 32971362 Free PMC article.
Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.
van de Wetering C, Aboushousha R, Manuel AM, Chia SB, Erickson C, MacPherson MB, van der Velden JL, Anathy V, Dixon AE, Irvin CG, Poynter ME, van der Vliet A, Wouters EFM, Reynaert NL, Janssen-Heininger YMW. van de Wetering C, et al. Among authors: chia sb. J Immunol. 2020 Feb 15;204(4):763-774. doi: 10.4049/jimmunol.1901086. Epub 2020 Jan 10. J Immunol. 2020. PMID: 31924651 Free PMC article.
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, Seward DJ, Janssen-Heininger YMW. Aboushousha R, et al. Among authors: chia sb. FASEB J. 2021 May;35(5):e21525. doi: 10.1096/fj.202002687RR. FASEB J. 2021. PMID: 33817836 Free PMC article.
IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease.
Qian X, Aboushousha R, van de Wetering C, Chia SB, Amiel E, Schneider RW, van der Velden JLJ, Lahue KG, Hoagland DA, Casey DT, Daphtary N, Ather JL, Randall MJ, Aliyeva M, Black KE, Chapman DG, Lundblad LKA, McMillan DH, Dixon AE, Anathy V, Irvin CG, Poynter ME, Wouters EFM, Vacek PM, Henket M, Schleich F, Louis R, van der Vliet A, Janssen-Heininger YMW. Qian X, et al. Among authors: chia sb. J Allergy Clin Immunol. 2018 Aug;142(2):435-450.e10. doi: 10.1016/j.jaci.2017.08.043. Epub 2017 Nov 3. J Allergy Clin Immunol. 2018. PMID: 29108965 Free PMC article.
13 results