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Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
Shah OS, Nasrazadani A, Foldi J, Atkinson JM, Kleer CG, McAuliffe PF, Johnston TJ, Stallaert W, da Silva EM, Selenica P, Dopeso H, Pareja F, Mandelker D, Weigelt B, Reis-Filho JS, Bhargava R, Lucas PC, Lee AV, Oesterreich S. Shah OS, et al. Among authors: kleer cg. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2322068121. doi: 10.1073/pnas.2322068121. Epub 2024 Jul 23. Proc Natl Acad Sci U S A. 2024. PMID: 39042692 Free PMC article.
BRCA1 regulates human mammary stem/progenitor cell fate.
Liu S, Ginestier C, Charafe-Jauffret E, Foco H, Kleer CG, Merajver SD, Dontu G, Wicha MS. Liu S, et al. Among authors: kleer cg. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1680-5. doi: 10.1073/pnas.0711613105. Epub 2008 Jan 29. Proc Natl Acad Sci U S A. 2008. PMID: 18230721 Free PMC article.
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Rhodes DR, Ateeq B, Cao Q, Tomlins SA, Mehra R, Laxman B, Kalyana-Sundaram S, Lonigro RJ, Helgeson BE, Bhojani MS, Rehemtulla A, Kleer CG, Hayes DF, Lucas PC, Varambally S, Chinnaiyan AM. Rhodes DR, et al. Among authors: kleer cg. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10284-9. doi: 10.1073/pnas.0900351106. Epub 2009 Jun 1. Proc Natl Acad Sci U S A. 2009. PMID: 19487683 Free PMC article.
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM. Robinson DR, et al. Among authors: kleer cg. Nat Med. 2011 Nov 20;17(12):1646-51. doi: 10.1038/nm.2580. Nat Med. 2011. PMID: 22101766 Free PMC article.
EZH2 expands breast stem cells through activation of NOTCH1 signaling.
Gonzalez ME, Moore HM, Li X, Toy KA, Huang W, Sabel MS, Kidwell KM, Kleer CG. Gonzalez ME, et al. Among authors: kleer cg. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3098-103. doi: 10.1073/pnas.1308953111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516139 Free PMC article.
161 results