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The Genome-wide DNA methylation changes in gastrointestinal surgery patients with and without postoperative delirium: Evidence of immune process in its pathophysiology.
Nishizawa Y, Yamanashi T, Nishiguchi T, Kajitani N, Miura A, Matsuo R, Tanio A, Yamamoto M, Sakamoto T, Fujiwara Y, Thompson K, Malicoat J, Yamanishi K, Seki T, Kanazawa T, Iwata M, Shinozaki G. Nishizawa Y, et al. Among authors: nishiguchi t. J Psychiatr Res. 2024 Sep;177:249-255. doi: 10.1016/j.jpsychires.2024.07.013. Epub 2024 Jul 20. J Psychiatr Res. 2024. PMID: 39043004
Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression.
Kajitani N, Iwata M, Miura A, Tsunetomi K, Yamanashi T, Matsuo R, Nishiguchi T, Fukuda S, Nagata M, Shibushita M, Yamauchi T, Pu S, Shirayama Y, Watanabe K, Kaneko K. Kajitani N, et al. Among authors: nishiguchi t. Neuropsychopharmacol Rep. 2020 Jun;40(2):157-165. doi: 10.1002/npr2.12099. Epub 2020 Mar 3. Neuropsychopharmacol Rep. 2020. PMID: 32125791 Free PMC article.
Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model.
Yamanashi T, Iwata M, Shibushita M, Tsunetomi K, Nagata M, Kajitani N, Miura A, Matsuo R, Nishiguchi T, Kato TA, Setoyama D, Shirayama Y, Watanabe K, Shinozaki G, Kaneko K. Yamanashi T, et al. Among authors: nishiguchi t. Sci Rep. 2020 Dec 10;10(1):21629. doi: 10.1038/s41598-020-78410-2. Sci Rep. 2020. PMID: 33303808 Free PMC article.
Stress increases blood beta-hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly in a rodent model.
Nishiguchi T, Iwata M, Kajitani N, Miura A, Matsuo R, Murakami S, Nakada Y, Pu S, Shimizu Y, Tsubakino T, Yamanashi T, Shinozaki G, Tsubota J, Shirayama Y, Watanabe K, Kaneko K. Nishiguchi T, et al. Neuropsychopharmacol Rep. 2021 Jun;41(2):159-167. doi: 10.1002/npr2.12164. Epub 2021 Feb 20. Neuropsychopharmacol Rep. 2021. PMID: 33609086 Free PMC article.
Genome-wide DNA methylation analysis of post-operative delirium with brain, blood, saliva, and buccal samples from neurosurgery patients.
Wahba NE, Nishizawa Y, Marra PS, Yamanashi T, Crutchley KJ, Nagao T, Shibata K, Nishiguchi T, Cho H, Howard MA 3rd, Kawasaki H, Hefti M, Kanazawa T, Shinozaki G. Wahba NE, et al. Among authors: nishiguchi t. J Psychiatr Res. 2022 Dec;156:245-251. doi: 10.1016/j.jpsychires.2022.10.023. Epub 2022 Oct 9. J Psychiatr Res. 2022. PMID: 36270064 Free PMC article.
Bispectral EEG (BSEEG) Algorithm Captures High Mortality Risk Among 1,077 Patients: Its Relationship to Delirium Motor Subtype.
Nishizawa Y, Yamanashi T, Saito T, Marra P, Crutchley KJ, Wahba NE, Malicoat J, Shibata K, Nishiguchi T, Lee S, Cho HR, Kanazawa T, Shinozaki G. Nishizawa Y, et al. Among authors: nishiguchi t. Am J Geriatr Psychiatry. 2023 Sep;31(9):704-715. doi: 10.1016/j.jagp.2023.03.002. Epub 2023 Mar 8. Am J Geriatr Psychiatry. 2023. PMID: 37003894
The Bispectral Electroencephalography Method Quantifies Postoperative Delirium-Like States in Young and Aged Male Mice After Head-Mount Implantation Surgery.
Nishiguchi T, Shibata K, Yamanishi K, Dittrich MN, Islam NY, Patel S, Phuong NJ, Marra PS, Malicoat JR, Seki T, Nishizawa Y, Yamanashi T, Iwata M, Shinozaki G. Nishiguchi T, et al. J Gerontol A Biol Sci Med Sci. 2024 Aug 1;79(8):glae158. doi: 10.1093/gerona/glae158. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38877811
220 results