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183 results

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Page 1
Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease.
Rissman RA, Donohue MC, Langford O, Raman R, Abdel-Latif S, Yaari R, Holdridge KC, Sims JR, Molina-Henry D, Jimenez-Maggiora G, Johnson KA, Aisen PS, Sperling RA. Rissman RA, et al. Among authors: sims jr. J Prev Alzheimers Dis. 2024;11(4):823-830. doi: 10.14283/jpad.2024.134. J Prev Alzheimers Dis. 2024. PMID: 39044490 Free PMC article. Clinical Trial.
Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies.
Sperling RA, Donohue MC, Rissman RA, Johnson KA, Rentz DM, Grill JD, Heidebrink JL, Jenkins C, Jimenez-Maggiora G, Langford O, Liu A, Raman R, Yaari R, Holdridge KC, Sims JR, Aisen PS. Sperling RA, et al. Among authors: sims jr. J Prev Alzheimers Dis. 2024;11(4):802-813. doi: 10.14283/jpad.2024.122. J Prev Alzheimers Dis. 2024. PMID: 39044488 Free PMC article. Clinical Trial.
Pre-Randomization Predictors of Study Discontinuation in a Preclinical Alzheimer's Disease Randomized Controlled Trial.
Raman R, Hussen K, Donohue MC, Ernstrom K, Holdridge KC, Langford O, Molina-Henry DP, Pierce AL, Sims JR, Smith A, Yaari R, Aisen PS, Sperling R, Grill JD. Raman R, et al. Among authors: sims jr. J Prev Alzheimers Dis. 2024;11(4):874-880. doi: 10.14283/jpad.2024.136. J Prev Alzheimers Dis. 2024. PMID: 39044496 Free PMC article. Clinical Trial.
Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.
Aye S, Johansson G, Hock C, Lannfelt L, Sims JR, Blennow K, Frederiksen KS, Graff C, Molinuevo JL, Scheltens P, Palmqvist S, Schöll M, Wimo A, Kivipelto M, Handels R, Frölich L, Zilka N, Tolar M, Johannsen P, Jönsson L, Winblad B. Aye S, et al. Among authors: sims jr. J Prev Alzheimers Dis. 2025 Jan;12(1):100022. doi: 10.1016/j.tjpad.2024.100022. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800469 Free article.
MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.
Lloyd C, Freskgård PO, Newton P, Lowne D, Nickson A, Bogstedt A, Eketjäll S, Höglund K, Gustavsson S, Welsh F, Chessell T, McFarlane M, Bhat RV, Turner R, Perkinton MS, Santisteban Valencia Z, Lindqvist E, Pomfret M, Dudley AD, Vaughan TJ, Groves MT, Natanegara F, Feng Y, Sims JR, Proctor NK, Dage JL, Shering C, Tan K, Ostenfeld T, Billinton A, Chessell IP. Lloyd C, et al. Among authors: sims jr. Alzheimers Dement. 2024 Nov;20(11):7762-7776. doi: 10.1002/alz.14238. Epub 2024 Sep 25. Alzheimers Dement. 2024. PMID: 39319998 Free PMC article.
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network–Trials Unit. Wagemann O, et al. Among authors: sims jr. JAMA Neurol. 2024 Jun 1;81(6):582-593. doi: 10.1001/jamaneurol.2024.0991. JAMA Neurol. 2024. PMID: 38683602 Free PMC article. Clinical Trial.
183 results