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Role of Mitochondrial and Cytosolic Folylpolyglutamate Synthetase in One-Carbon Metabolism and Antitumor Efficacy of Mitochondrial-Targeted Antifolates.
Mol Pharmacol. 2024 Sep 17;106(4):173-187. doi: 10.1124/molpharm.124.000912.
Mol Pharmacol. 2024.
PMID: 39048308
Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria.
Nayeen MJ, Katinas JM, Magdum T, Shah K, Wong JE, O'Connor CE, Fifer AN, Wallace-Povirk A, Hou Z, Matherly LH, Dann CE 3rd, Gangjee A.
Nayeen MJ, et al. Among authors: magdum t.
J Med Chem. 2023 Aug 24;66(16):11294-11323. doi: 10.1021/acs.jmedchem.3c00763. Epub 2023 Aug 15.
J Med Chem. 2023.
PMID: 37582241
Free PMC article.
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