Rubin BP - Search Results

1

CDK9 Inhibition by Dinaciclib Is a Therapeutic Vulnerability in Epithelioid Hemangioendothelioma.

Pobbati AV, Burtscher A, Rajaram Siva N, Hallett A, Romigh T, Che K, Zhao B, Coker JA, Wang N, Stauffer SR, Rubin BP. Pobbati AV, et al. Among authors: rubin bp. Clin Cancer Res. 2024 Sep 13;30(18):4179-4189. doi: 10.1158/1078-0432.CCR-24-1097. Clin Cancer Res. 2024. PMID: 39052240

2

Olaratumab Exerts Antitumor Activity in Preclinical Models of Pediatric Bone and Soft Tissue Tumors through Inhibition of Platelet-Derived Growth Factor Receptor α.

Lowery CD, Blosser W, Dowless M, Knoche S, Stephens J, Li H, Surguladze D, Loizos N, Luffer-Atlas D, Oakley GJ 3rd, Guo Q, Iyer S, Rubin BP, Stancato L. Lowery CD, et al. Among authors: rubin bp. Clin Cancer Res. 2018 Feb 15;24(4):847-857. doi: 10.1158/1078-0432.CCR-17-1258. Epub 2017 Nov 30. Clin Cancer Res. 2018. PMID: 29191969

3

Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.

Lowery CD, Dowless M, Renschler M, Blosser W, VanWye AB, Stephens JR, Iversen PW, Lin AB, Beckmann RP, Krytska K, Cole KA, Maris JM, Hawkins DS, Rubin BP, Kurmasheva RT, Houghton PJ, Gorlick R, Kolb EA, Kang MH, Reynolds CP, Erickson SW, Teicher BA, Smith MA, Stancato LF. Lowery CD, et al. Among authors: rubin bp. Clin Cancer Res. 2019 Apr 1;25(7):2278-2289. doi: 10.1158/1078-0432.CCR-18-2728. Epub 2018 Dec 18. Clin Cancer Res. 2019. PMID: 30563935 Free PMC article.

4

Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex.

Pobbati AV, Rubin BP. Pobbati AV, et al. Among authors: rubin bp. Molecules. 2020 Dec 18;25(24):6001. doi: 10.3390/molecules25246001. Molecules. 2020. PMID: 33352993 Free PMC article. Review.

5

WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis.

Seavey CN, Pobbati AV, Hallett A, Ma S, Reynolds JP, Kanai R, Lamar JM, Rubin BP. Seavey CN, et al. Among authors: rubin bp. Genes Dev. 2021 Apr 1;35(7-8):512-527. doi: 10.1101/gad.348220.120. Epub 2021 Mar 25. Genes Dev. 2021. PMID: 33766982 Free PMC article.

6

Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.

Gibault F, Sturbaut M, Coevoet M, Pugnière M, Burtscher A, Allemand F, Melnyk P, Hong W, Rubin BP, Pobbati AV, Guichou JF, Cotelle P, Bailly F. Gibault F, et al. Among authors: rubin bp. ChemMedChem. 2021 Sep 16;16(18):2823-2844. doi: 10.1002/cmdc.202100153. Epub 2021 Jul 1. ChemMedChem. 2021. PMID: 34032019

7

Inhibition of PI3K and MAPK pathways along with KIT inhibitors as a strategy to overcome drug resistance in gastrointestinal stromal tumors.

Gupta A, Ma S, Che K, Pobbati AV, Rubin BP. Gupta A, et al. Among authors: rubin bp. PLoS One. 2021 Jul 29;16(7):e0252689. doi: 10.1371/journal.pone.0252689. eCollection 2021. PLoS One. 2021. PMID: 34324512 Free PMC article.

8

Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex.

Che K, Pobbati AV, Seavey CN, Fedorov Y, Komar AA, Burtscher A, Ma S, Rubin BP. Che K, et al. Among authors: rubin bp. PLoS One. 2022 Apr 13;17(4):e0266143. doi: 10.1371/journal.pone.0266143. eCollection 2022. PLoS One. 2022. PMID: 35417479 Free PMC article.

9

The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras-MAPK Signaling in Epithelioid Hemangioendothelioma.

Ma S, Kanai R, Pobbati AV, Li S, Che K, Seavey CN, Hallett A, Burtscher A, Lamar JM, Rubin BP. Ma S, et al. Among authors: rubin bp. Clin Cancer Res. 2022 Jul 15;28(14):3116-3126. doi: 10.1158/1078-0432.CCR-22-0421. Clin Cancer Res. 2022. PMID: 35443056 Free PMC article. Clinical Trial.

10

Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ-CAMTA1 Fusion Driven Sarcoma.

Seavey CN, Pobbati AV, Rubin BP. Seavey CN, et al. Among authors: rubin bp. Cancers (Basel). 2022 Jun 16;14(12):2980. doi: 10.3390/cancers14122980. Cancers (Basel). 2022. PMID: 35740643 Free PMC article. Review.

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