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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system.
Tiwari V, Prajapati B, Asare Y, Damkou A, Ji H, Liu L, Naser N, Gouna G, Leszczyńska KB, Mieczkowski J, Dichgans M, Wang Q, Kawaguchi R, Shi Z, Swarup V, Geschwind DH, Prinz M, Gokce O, Simons M. Tiwari V, et al. Among authors: geschwind dh. Immunity. 2024 Sep 10;57(9):2173-2190.e8. doi: 10.1016/j.immuni.2024.07.001. Epub 2024 Jul 24. Immunity. 2024. PMID: 39053462 Free article.
Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma.
Patel KS, Tessema KK, Kawaguchi R, Dudley L, Alvarado AG, Muthukrishnan SD, Perryman T, Hagiwara A, Swarup V, Liau LM, Wang AC, Yong W, Geschwind DH, Nakano I, Goldman SA, Everson RG, Ellingson BM, Kornblum HI. Patel KS, et al. Among authors: geschwind dh. Neurooncol Adv. 2024 Jan 25;6(1):vdae005. doi: 10.1093/noajnl/vdae005. eCollection 2024 Jan-Dec. Neurooncol Adv. 2024. PMID: 38616896 Free PMC article.
A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex.
Huuki-Myers LA, Spangler A, Eagles NJ, Montgomery KD, Kwon SH, Guo B, Grant-Peters M, Divecha HR, Tippani M, Sriworarat C, Nguyen AB, Ravichandran P, Tran MN, Seyedian A; PsychENCODE Consortium†; Hyde TM, Kleinman JE, Battle A, Page SC, Ryten M, Hicks SC, Martinowich K, Collado-Torres L, Maynard KR; PsychENCODE Consortium. Huuki-Myers LA, et al. Science. 2024 May 24;384(6698):eadh1938. doi: 10.1126/science.adh1938. Epub 2024 May 24. Science. 2024. PMID: 38781370 Free PMC article.
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics.
Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, Robinson J, Gaus SE, Spina S, Lee EB, Grinberg LT, Vinters H, Trojanowski JQ, Seeley WW, Malhotra D, Geschwind DH. Rexach JE, et al. Among authors: geschwind dh. bioRxiv [Preprint]. 2023 Sep 30:2023.09.29.560245. doi: 10.1101/2023.09.29.560245. bioRxiv. 2023. Update in: Cell. 2024 Oct 3;187(20):5753-5774.e28. doi: 10.1016/j.cell.2024.08.019 PMID: 37808727 Free PMC article. Updated. Preprint.
Acute rapamycin treatment reveals novel mechanisms of behavioral, physiological, and functional dysfunction in a maternal inflammation mouse model of autism and sensory over-responsivity.
Le Belle JE, Condro M, Cepeda C, Oikonomou KD, Tessema K, Dudley L, Schoenfield J, Kawaguchi R, Geschwind D, Silva AJ, Zhang Z, Shokat K, Harris NG, Kornblum HI. Le Belle JE, et al. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602602. doi: 10.1101/2024.07.08.602602. bioRxiv. 2024. PMID: 39026891 Free PMC article. Preprint.
Comprehensive functional genomic resource and integrative model for the human brain.
Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K, Hoffman GE, Kalayci S, Gümüş ZH, Crawford GE; PsychENCODE Consortium; Roussos P, Akbarian S, Jaffe AE, White KP, Weng Z, Sestan N, Geschwind DH, Knowles JA, Gerstein MB. Wang D, et al. Among authors: geschwind dh. Science. 2018 Dec 14;362(6420):eaat8464. doi: 10.1126/science.aat8464. Science. 2018. PMID: 30545857 Free PMC article.
Author Correction: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes.
Farrell K, Humphrey J, Chang T, Zhao Y, Leung YY, Kuksa PP, Patil V, Lee WP, Kuzma AB, Valladares O, Cantwell LB, Wang H, Ravi A, De Sanctis C, Han N, Christie TD, Afzal R, Kandoi S, Whitney K, Krassner MM, Ressler H, Kim S, Dangoor D, Iida MA, Casella A, Walker RH, Nirenberg MJ, Renton AE, Babrowicz B, Coppola G, Raj T, Höglinger GU, Müller U, Golbe LI, Morris HR, Hardy J, Revesz T, Warner TT, Jaunmuktane Z, Mok KY, Rademakers R, Dickson DW, Ross OA, Wang LS, Goate A, Schellenberg G, Geschwind DH; PSP Genetics Study Group; Crary JF, Naj A. Farrell K, et al. Among authors: geschwind dh. Nat Commun. 2024 Nov 13;15(1):9828. doi: 10.1038/s41467-024-53617-3. Nat Commun. 2024. PMID: 39537593 Free PMC article. No abstract available.
610 results